Title: HPLC fingerprint for Fufang Xueshuantong Granules
Abstract:Objective To establish the HPLC fingerprint for Fufang Xueshuangtong Granules for the quality control. Methods HPLC was performed on Thermo ODS-2 C18column(4. 6 mm × 150 mm,5 μm) coupled with a C18gua...Objective To establish the HPLC fingerprint for Fufang Xueshuangtong Granules for the quality control. Methods HPLC was performed on Thermo ODS-2 C18column(4. 6 mm × 150 mm,5 μm) coupled with a C18guard column,and the mobile phase was consisted of acetonitrile and 0. 1% H3PO4in gradient elution mode at 270 nm with detection time of 60 minutes. The similarity evaluation system for chromatographic fingerprint of TCM(2009) was employed on 15 samples. Results 14 common peaks were observed in the fingerprints,and the similarity between peaks was more than 0. 90. Conclusion The method is simple,accurate and sensitive. This HPLC fingerprint may be used for the quality control of Fufang Xueshuangtong Granules.Read More
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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