Title: Correlation between lipids metabolism and coronary artery disease in postmenopause female patients
Abstract: Objective: To investigate the lipids profile of patients with coronary heart disease (CHD) in postmenopause females, and explore the relation between serum lipids and coronary artery disease. Method: Ninety four postmenopause female CHD documented by angiography were selected as CHD group and 100 normal female subjects as control. Result: The serum levels of triglyceride (TG) and low density lipoprotein cholesterol (LDL C) in CHD group were higher than those in control group, but the levels of apolipoprotein A 1 (apo A 1) and high density lipoprotein cholesterol (HDL C) in CHD group were much lower than those in control group, while the level of TC in CHD group was slightly higher than that in control group.Multivarietic regression analysis showed that the valuable indicators were apoA 1 and LDL C. Among CHD group, 53.2 % patients were complicated with high TG; and among patients with high TG, there were 29 cases (58%) suffered from stenotic losion in 2 or 3 branches of coronary artery. While in patients with normal level of TG, only 13 cases ( 29.5 %) suffered from similar condition. Conclusion: In postmenopause females, hypertriglyceridemia, high level of LDL C, low level of HDL C and apoA 1 are risk factors of CHD. LDL C and apo A 1 may promote CHD more directly. The lesion of coronary artery is more severe in patients with CHD who has hypertriglyceridemia.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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