Title: Clinical observation of Actilyse in treatment of acute cerebral infarction with hemorrhage
Abstract: Objective To explore and evaluate the clinical significance and relevant influencing factors of the application of Actilyse(rt-PA)in the treatment of 6 h acute cerebral infarction wutg hemorrhage.Methods Meet the criteria for inclusion of 209 patients were divided randomly into three groups,A group were given 0.9 mg/kg rt-PA;B group were given 0.7 mg/kg rt-PA;C group as control group,while the three groups were divided into G Messiah group(A1,B1,C1) and non G Messiah group(A2,B2,C2).Through CSS and BI on thrombolytic therapy after thrombolysis,24 h,3d,7d,90d efficacy evaluation.Results The group A and B of the total incidence of bleeding,48h and 14d total cerebral hemorrhage rates were higher than those of group C,there is significant difference(P0.05).Group A,B and C group in symptomatic intracranial hemorrhage rate had no significant difference(P0.05).Group A and B of the 90 d significant efficiency and 90d recovery rate were higher than those in group C,there is significant difference(P0.05).Group A and B of the 90 d fatality rates were lower than C group,there is significant difference(P0.05).Group A and B above all between analytical results had no significant difference(P0.05),G Messiah greup and non G Messiah group were compared between groups,there is no significant difference(P0.05).Conclusions The application of rt-PA for intravenous thrombolysis in acute cerebral infarction 6h will increase bleeding risk,but can enhance the therapeutic effect and reduce the case fatality rate,prompt application of rt-PA in 6h intravenous thrombolysis in treatment of acute cerebral infarction area is feasible,the applied dose to 0.7 mg/kg suitable.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot