Title: Norovirus infection and diarrhea from 2007 to 2009 in Tianjin,China
Abstract: Objective To investigate the norovirus infection status among patients with diarrhea and its clinical and epidemiological characteristics in Tianjin city,China.MethodsFive hospitals at different districts in Tianjin city were selected.The diarrhea patients were inquired to fill out a clinical and epidemiological questionnaire;and their stool samples were collected for detection of norovirus antigen by ELISA and genotyping by RT-PCR.ResultsAmong 1 085 diarrhea patients,129 patients were found norovirus antigen positive(11.89%) with the highest rate in the group of under five years(23.05%).The incidence rate of norovirus diarrhea was higher in winter and spring but no significant district clusterings.Out of the 129 noroviruses positive specimens,GⅡ-type accounts for 80.62%.The norovirus antigen positive rate among scattered children patients was 22.60%.Norovirus can be detected within 15 days from the onset of diarrhea.Clinically,norovirus diarrhea(97.25% with detectable white blood cells in the stool specimen;WBC≤10/HPF) is more severe than non-norovirus patients.ConclusionsNorovirus diarrhea in Tianjin is a common public health problem and measures should be taken,especially for children under 5 years old.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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