Title: Correlation between carotid artery intima-media thickness and traditional factors of coronary artery disease risk
Abstract: Objective To evaluate the relationship between carotid artery intima-media thickness(IMT)and risk factors of coronary arteries disease.Methods A total of 769 subjects were randomly selected from natural multitude for physical examination in Fuwai hospital.Carotid artery IMT were measured by high-frequency ultrasound,and plaque was defined when the value of IMT was higher than 1.2 mm.Meanwhile,the location,quantity and properties of the carotid atherosclerotic plaques were observed and risk factors of coronary heart disease were investigated.Results The measurement of every point of carotid artery had no significant difference between left and right(the mean value of every point of the left were(0.69±0.14),(0.68±0.15),(1.29±0.25) and (0.64±0.14)mm,and those of right were(0.68±0.15),(0.67±0.14),(1.30±0.24) and (0.65±0.13)mm respectively,t=1.35,1.34,0.83,1.47,P0.05).The mean value of IMT in bilateral carotid artery crotch was significantly higher than those of other points(the mean value of every point were(0.68±0.15),(0.67±0.14),(1.30±0.24),(0.65±0.13)mm,t=3.55,3.16,3.28,P0.01).Atherosclerotic plaques positive rate of male were significantly higher than that of female[(45.4% ,189/417)vs(29.2%,103/352)respectively,χ2= 20.91,P0.01]and tended to increase with increasing age in both genders(female respectively 7.1%,36.9% and86.4%,χ2= 19.31,P0.01;male respectively 10.5%,67.6%,89.6%,χ2=21.45,P0.01).Group45-55Y atherosclerotic plaques incidence rate of male was significantly higher than that of female[(67.6%,84/124)vs(39.6%,46/115)respectively,χ2= 18.51,P0.01].Logistic analysis revealed that the significant independent determinants of carotid artery plaques in male group were age,hypertension,smoking,diabetes,hyperlipidemia and familial history(OR=1.09,1.39,1.46,1.92,1.45,1.48,all P0.05),and in female group were age,hypertension,diabetes,hyperlipidemia and familial history(OR=1.12,2.58,1.46,1.45,all P0.01).Conclusions Carotid artery IMT and risk factors of coronary heart disease are closely related.The value of IMT is able to forecast the occurrence of coronary heart disease.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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