Title: Carotid artery intima media thickness as a predictor of coronary artery disease in population of North Karnataka, India
Abstract: Coronary artery disease (CAD) is a major cause of morbidity and mortality in developed and developing world .The important predisposing factor to coronary artery disease is atherosclerosis of coronary arteries. Carotid artery intima media thickness (IMT) can be used as a measure of generalized atherosclerosis. Ultrasound B mode serves as a simple ,safe, cost effective and noninvasive method for measuring carotid artery intima media thickness, hence this study was undertaken to evaluate association of carotid IMT in prediction of CAD in local population. Carotid IMT was measured with a Bmode USG in 50 cases of coronary artery disease and 50 age and sex matched controls. IMT values more than 0.8 mm were labeled as significant for correlating the association between IMT and CAD. On univariate analysis mean IMT was 1.098±0.2938 as against 0.606±0.1530 which was statistically significant with a p value of 0.001. In subgroup analysis, the mean IMT in hypertensive cases was higher than the controls and was statistically significant and also the mean IMT in diabetic cases was significantly higher than the non diabetic controls. A statistically significant increase in carotid IMT was also observed in smokers than in nonsmoking controls. Carotid artery intima media thickness can be measured by B- mode ultrasound which is a simple, non invasive and reproducible technique. Carotid artery intima media thickness is a marker of atherosclerosis which is strongly associated with traditional risk factors and could be used as asurrogate marker in prediction of atherosclerosis and CAD in Indians.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot