Title: Efficacy of Zhenjujiangya Tablet Combined with Valsartan in the Treatment of Hypertension(Upper Hyperactivity of Liver Yang) Patients
Abstract: Objective:To study the efficacy of Zhenjujiangya tablet combined with angiotensin Ⅱ receptor blocker( ARB) valsartan in the treatment of hypertension( upper hyperactivity of liver yang). Methods:A total of 60 patients with primary hypertension syndrome( upper hyperactivity of liver yang) were randomly divided into treatment group( Zhenjujiangya tablet + valsartan,n = 32) and control group( hydrochlorothiazide + valsartan,n = 28). At 8 weeks after the treatment,dynamic blood pressure,blood pressure variability and TCM symptom score were observed. Results: After treatment,compared with the control group,SBP,d-SBP,n-SBP in the treatment group were significantly lower( P 0. 05),whereas DBP,d-DBP,n-DBP had no significant difference( P 0. 05). The blood pressure variability d-SBPV and n-SBPV in the treatment group were significantly lower than those in the control group( P 0. 01),but d-DBPV,n-DBPV had no significant difference between the two groups( P 0. 05). In the treatment group,TCM symptoms( dizziness,headache,irritability) scores were significantly lower( P 0. 05)than those in the control group,but limb symptoms integral differences had no difference between the two groups( P 0. 05).Conclusions: Zhenjujiangya tablet in combination with valsartan therapy in patients with hypertension(upper hyperactivity of liver yang)can not only effectively reduce the blood pressure and improve blood pressure variability,but also improve the clinical symptoms of patients.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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