Title: INFLUENCE OF SIMVASTATIN ON THE LEVEL OF ESSENTIAL HYPERTENSION
Abstract: [Objective] To observe the clinical therapeutic effect and safety of Simvastatin combined with Valsartan in the long-term treatment of slight and midrange essential hypertension.[Methods]103 patients with slight and midrange essential hypertension were divided randomly into treatment group(n=53)and control group(n=50).And the treatment group was treated with Simvastatin and Valsartan,while the control group was treated only with Valsartan.The effect was analyzed after 10 weeks.[Results]The overall effective rate in treatment group was 97.1% and control group was 84.0%,the effect difference of two groups had statistical significance(P﹤0.05).Before and after treatment,the clinical blood pressure and the averaged blood pressure during 24-hour,daytime and nighttime of two groups were reduced(P﹤0.01),and the TC and LDL-C were reduced(P﹤0.05)too.Compared with treatment group and control group after treatment,the clinical blood pressure and the averaged blood pressure during 24-hour,daytime and nighttime of two groups were reduced(P﹤0.05),the ratio of valley and peak in the treatment group was superior to the control group.[Conclusion]It is effective to reduce the blood pressure in treating hypertension with statins,especially it is the best choice to the hypertensive patients with hyperlipemia.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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