Title: Expression of DPC4 in thyroid carcinoma and its clinical significance
Abstract: Objective To study the expression of DPC4 in human thyroid carcinoma specimens and its clinical significance.Methods Immunohistochemical SP method was used to detect the expressions of DPC4 in 30 tissues of thyroid carcinoma and 30 tissues of normal thyroid.Results The expression of DPC4 protein in tissues of thyroid carcinoma was obviously lower than that of normal thyroid tissues.The expression of DPC4 was reversely related to the clinic TNM stage,the lymph node metastasis and the type of pathology.Conclusion Low-expression of DPC4 protein plays an important role in occurrence and metastasis of thyroid carcinoma.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot