Publication Information

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'https://openalex.org/W2417116685', 'https://openalex.org/W2409123310', 'https://openalex.org/W2390087765', 'https://openalex.org/W2381434129', 'https://openalex.org/W2371625977', 'https://openalex.org/W2371619481', 'https://openalex.org/W2367924323', 'https://openalex.org/W2366215831', 'https://openalex.org/W2361167702', 'https://openalex.org/W2352313277', 'https://openalex.org/W2351884508', 'https://openalex.org/W2091836599', 'https://openalex.org/W2085224105', 'https://openalex.org/W2079061680', 'https://openalex.org/W2072262710', 'https://openalex.org/W1670951778'], 'abstract_inverted_index': {'OBJECTIVE': [0], 'To': [1], 'investigate': [2], 'the': [3, 33, 75, 106, 125], 'mutation': [4, 104, 115], 'characteristics': [5], 'of': [6, 12, 20, 24, 35, 47, 53, 65, 82, 88, 99, 128], 'katG': [7, 25, 69, 117], 'gene': [8, 26, 70], 'in': [9, 16, 27, 38, 97, 112, 116, 131], 'isoniazid(INH)-resistant': [10], 'strains': [11, 29, 46, 49, 52, 59, 67, 84, 90, 111], 'Mycobacterium': [13], 'tuberculosis': [14, 36], 'isolated': [15, 31], 'Hefei.METHODS': [17], 'Aanlyze': [18], 'sequences': [19], '731bp': [21], 'DNA': [22, 41], 'fragment': [23], '86': [28], 'M.tuberculosis': [30], 'from': [32], 'sputum': [34], 'patients': [37], 'Hefei': [39], 'by': [40, 63], 'sequencing.RESULTS': [42], 'There': [43], 'were': [44, 60], '67': [45, 56], 'INH-resistant': [48, 57, 110], 'and': [50], '19': [51, 100], 'INH-susceptible': [54, 101], 'strains.In': [55], 'strains,61': [58], 'amplified': [61], 'successfully': [62], 'PCR,56': [64], '61(91.8%)INH-resistant': [66], 'had': [68, 85, 91], 'mutation,Sequencing': [71], 'results': [72], 'showed': [73], 'that': [74], 'mutations': [76], 'mainly': [77], 'located': [78], 'at': [79], '463-Arg(93.4%)and': [80], '315-Ser(42.6%).30': [81], '61(49.2%)INH-resistant': [83], 'combinative': [86], 'mutation;26': [87], '61(42.6%)INH-resistant': [89], 'point': [92], 'mutation.Arg4631eu': [93], 'was': [94], 'also': [95], 'present': [96], '15': [98], 'strains.CONCLUSION': [102], 'KatG315': [103], 'is': [105], 'main': [107], 'mechanism': [108], 'to': [109, 124], 'Hefei.463': [113], 'Arginine': [114], 'should': [118], 'be': [119], 'considered': [120], 'as': [121], 'polymorphism': [122], 'unrelated': [123], 'selective': [126], 'pressure': [127], 'drug': [129], 'treatment': [130], 'M.tuberculosis.': [132]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2371235186', 'counts_by_year': [], 'updated_date': '2024-12-08T16:13:09.062537', 'created_date': '2016-06-24'}