Title: The clinical value of HLA-B27 in the diagnosis of ankylosing spondyfitis
Abstract: Objective To explore the clinical value of HLA-B27 inpatients with ankylosing spondyfitis.Methods Using ELISA to detect the HLA-B27 of 450 healthy people(non-AS group),462 presumed AS patients(suspectable group)and 80 AS patients(AS group).ResultsThe positive rate of HLA-B27 of non-AS patients,presumed AS patients and AS patients was 3.3%,48.9%and 92.5%respectively.The positive rate of HLA-B27 of AS patients was significantly higher than that of non-AS patients(P0.01).The positive rate of HLA-B27 of AS patients was significantly higher than that of presumed AS patients(P0.01).Conclusion There is positive correlation between AS and HLA-B27.It is very important for the early diagnosis of AS.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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