Title: Study on the preventive effect of mather and infant vertical transmison for HBV by HBIG
Abstract: Objective:To explore the preventive effect of mathernofatal Hepatitis B virus(HBV) transmission after pregnant women carring HBsAg and their newborns have been passive immunized Hepatitis B immunoglobulin (HBIG).Methods:Groups A (n=66),which HBIG 200 IU was given monthly in late pregnancy;Group B (n=68),which abtained only common antenatal care.The newborns were also divided into three Groups :Group Ⅰand Group Ⅱ abtained both HBIG and HBVac,and Group Ⅲ abtained HBVac only.Results :The positive rate of HBsAg of newborns (age≤24h) in Group A was significantly lower than that in Group B.As the infants were 6 months old,the HBsAb positive rate of infants was Group Ⅰ Group Ⅱ Group Ⅲ.Conclusion:The pregnant women carring HBsAg given HBIG monthly during late pregnancy can effectively reduce the positive rate of HBsAg of newborns,The pregnant women given HBIG monthly during late pregnancy and offsprings abtained HBIG nad HBVac as well can effectively prove the positive rate of HBsAb of 6 moths infants.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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