Title: Multiple Vertebral Compression Fracture:Benign and Malignant MRI Differential Diagnosis
Abstract: Objective To distinguish benign from malignant multiple vertebral collapses.Methods 171 vertebral collapses (77 benign,94 malignancy) were studied in 58 patients with T 1WI,T 2/T 2 WI,contrast enhancement T 1WI with fat saturation.Pathologic result was available in 16 vertebras,including 10 malignancy and 6 benign.The remaining patients were performed 3~6 months follow-up to confirm the final diagnosis.The following MR characteristics were reviewed:(1)The shape and distribution of abnormal signal intensity.(2)The shape of antero-or poster-border of compressive vertebral body.(3)Paravertebral soft tissue mass.(4)The change of lesions signal intensity on T 1WI,T 2WI and contrast enhanced MRI with fat saturation.(5)Signal intensity increasing ratio after contrast enhancement.Results The malignant vertebral compression fractures showed as the punch or patchy low signal intensity on T 1WI distributing anywhere in the compressive body and enhancement.It had the convex posterior cortex,pedicle involved,paravertebral soft tissue mass.The benign vertebral compression fractures showed as the band linear hypo-or-iso-intensity in end-plate,enhanced (acute fracture)or unenhanced(old fracture),retropulsion of posterior cortex,no pedicle involved and paravertebral soft tissue.Conclusion The most important MR characteristics for differentiation of malignant or bengin vertebral compression are the shapes and distributions of the abnormal signal intensities of vertebral collapses.The contrast enhancement T 1WI with fat saturation is helpful for imaging diagnosis.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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