Title: Clinical Implication of Subnormal Midwall Fraction Shortening of Left Ventricle in Patients with Essential Hypertension
Abstract: Objective To evaluate the relationship of subnormal midwall fractional shortening (mFS) with early damage of left ventricular(LV) systolic function and damage in target organs in patients with essential hypertension. Methods Radionuclide cineangiographic LV ejectoin fraction(EF) at rest and maximum dobatamine stress test, LV mass, urine protein were compared between groups with subnormal mFS and normal mFS. Results No difference of resting cardiac function between the two groups was found; subnormal mFS is associated with abnormal EF change of dobutamine stressed radionuclide ventriculography, increased LV mass, and increased urine protein. Conclusion Early damage of LV systolic function usually manifested as abnormal mFS, which often accompanied by impairment of LV and kidney.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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