Title: The Relation Between Left Ventricular Midwall Fractional Shortening and Left Ventricular Geometric Patterns in Hypertensive Patients
Abstract: Objective:To study the relationship between the alteration of myocardial contractility and cardiac function in hypertensive patients with different left ventricular geometry using the end systolic stress midwall fractional shortening. Methods:Left ventricular geometry and cardiac function was assessed by echocardiography in 117 cases of essential hypertension, with 45 normal cases as control. Patients were divided into four groups based on LVMI and RWT. Midwall fractional shortening(mFs) and meridional end systolic stress(MESS) were calculated. Results:The most serious impairment of left ventricular systolic function was shown in eccentric hypertrophy decreases in ejection fraction, fractional shortening and midwall fractional shortening. However myocardial contractility shown by end systolic stress midwall fractional shortening relation was worst in concentric hypertrophy group. The damage of diastolic function showed as EF slope was strongly correlated with the decreased myocardial contractility. Conclusion: The degree of myocardial contractility impairment was different in patients with different left ventricular geometry. Concentric hypertrophy of left ventricle compensated the reduction of myocardial contractility in some phases in order to maintain the normal systolic function.
Publication Year: 2000
Publication Date: 2000-01-01
Language: en
Type: article
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