Publication Information

{'id': 'https://openalex.org/W2367824721', 'doi': None, 'title': 'Mutations of rpoB gene in multi-drug resistant Mycobacterium tuberculosis isolates from Fujian province', 'display_name': 'Mutations of rpoB gene in multi-drug resistant Mycobacterium tuberculosis isolates from Fujian province', 'publication_year': 2013, 'publication_date': '2013-01-01', 'ids': {'openalex': 'https://openalex.org/W2367824721', 'mag': '2367824721'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZWJZ201307004.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764598783', 'display_name': 'Chinese Journal of Health Laboratory Technology', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5062806999', 'display_name': 'Liang Qing-f', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210140459', 'display_name': 'Center for Disease Control', 'ror': 'https://ror.org/04hsdam77', 'country_code': 'TW', 'type': 'facility', 'lineage': ['https://openalex.org/I4210140459']}, {'id': 'https://openalex.org/I184490438', 'display_name': 'Chinese Center For Disease Control and Prevention', 'ror': 'https://ror.org/04wktzw65', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I184490438', 'https://openalex.org/I4210127390', 'https://openalex.org/I4210151987']}], 'countries': ['CN', 'TW'], 'is_corresponding': True, 'raw_author_name': 'Liang Qing-f', 'raw_affiliation_strings': ['National Tuberculosis Reference Laboratory,National Center for TB Control and Prevention,Chinese Center for Disease Control and Prevention'], 'affiliations': [{'raw_affiliation_string': 'National Tuberculosis Reference Laboratory,National Center for TB Control and Prevention,Chinese Center for Disease Control and Prevention', 'institution_ids': ['https://openalex.org/I4210140459', 'https://openalex.org/I184490438']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5062806999'], 'corresponding_institution_ids': ['https://openalex.org/I4210140459', 'https://openalex.org/I184490438'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 65}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10038', 'display_name': 'Tuberculosis Research and Epidemiology', 'score': 0.9945, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10038', 'display_name': 'Tuberculosis Research and Epidemiology', 'score': 0.9945, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11316', 'display_name': 'Mycobacterium research and diagnosis', 'score': 0.9899, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/rpob', 'display_name': 'rpoB', 'score': 0.9932678}], 'concepts': [{'id': 'https://openalex.org/C2778340795', 'wikidata': 'https://www.wikidata.org/wiki/Q24782946', 'display_name': 'rpoB', 'level': 4, 'score': 0.9932678}, {'id': 'https://openalex.org/C2777975735', 'wikidata': 'https://www.wikidata.org/wiki/Q130971', 'display_name': 'Mycobacterium tuberculosis', 'level': 3, 'score': 0.722867}, {'id': 'https://openalex.org/C2781069245', 'wikidata': 'https://www.wikidata.org/wiki/Q12204', 'display_name': 'Tuberculosis', 'level': 2, 'score': 0.6312598}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.59953433}, {'id': 'https://openalex.org/C176944494', 'wikidata': 'https://www.wikidata.org/wiki/Q1415380', 'display_name': 'Point mutation', 'level': 4, 'score': 0.56191546}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.54828143}, {'id': 'https://openalex.org/C84597430', 'wikidata': 'https://www.wikidata.org/wiki/Q106227', 'display_name': 'Locus (genetics)', 'level': 3, 'score': 0.5314274}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.5287532}, {'id': 'https://openalex.org/C2994225774', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Gene mutation', 'level': 4, 'score': 0.52447605}, {'id': 'https://openalex.org/C98638677', 'wikidata': 'https://www.wikidata.org/wiki/Q2067051', 'display_name': 'Mutation rate', 'level': 3, 'score': 0.5006943}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.45360762}, {'id': 'https://openalex.org/C133936738', 'wikidata': 'https://www.wikidata.org/wiki/Q643839', 'display_name': 'Multiple drug resistance', 'level': 3, 'score': 0.42605293}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.40681595}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.3453974}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.34062272}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.18649772}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.038940877}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZWJZ201307004.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764598783', 'display_name': 'Chinese Journal of Health Laboratory Technology', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.83, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032646423', 'https://openalex.org/W2922080276', 'https://openalex.org/W2920431785', 'https://openalex.org/W2784517879', 'https://openalex.org/W2735847713', 'https://openalex.org/W2391013721', 'https://openalex.org/W2389698041', 'https://openalex.org/W2386583457', 'https://openalex.org/W2378447774', 'https://openalex.org/W2376163042', 'https://openalex.org/W2362466804', 'https://openalex.org/W2361028148', 'https://openalex.org/W2356503185', 'https://openalex.org/W2355651756', 'https://openalex.org/W2351513571', 'https://openalex.org/W2186397667', 'https://openalex.org/W2110731649', 'https://openalex.org/W2036200890', 'https://openalex.org/W1976082549', 'https://openalex.org/W1953528454'], 'abstract_inverted_index': {'Objective:To': [0], 'analyze': [1], 'the': [2, 42, 154], 'mutation': [3, 43, 64, 77, 118, 133, 157], 'characteristics': [4, 158], 'of': [5, 23, 50, 79, 96, 135, 146], 'rpoB': [6, 48, 80], 'gene': [7, 49, 81], 'in': [8, 14, 47, 67, 86, 107, 120], 'multi-drug': [9, 24], 'resistant(MDR)': [10], 'Mycobacterium': [11], 'tuberculosis': [12, 30, 75, 123, 149], 'isolates': [13, 31, 35, 124], 'Fujian': [15, 126], 'province,and': [16], 'provide': [17], 'molecular': [18], 'evidence': [19], 'for': [20, 142], 'fast': [21], 'diagnosis': [22, 140], 'resistant': [25], 'tuberculosis.': [26], 'Methods:Seventy-five': [27], 'MDR': [28, 73, 121, 147], 'M.': [29, 74, 122, 148], 'and': [32, 57, 101, 110, 130], '10': [33, 68], 'pan-susceptible': [34, 69], 'were': [36, 53, 128], 'selected': [37], 'from': [38, 125], '30': [39], 'survey': [40], 'sites,and': [41], 'patterns': [44], 'including': [45], 'RRDR': [46, 87, 108], 'these': [51], 'strains': [52], 'detected': [54, 66], 'by': [55], 'PCR': [56], 'sequenced': [58], 'with': [59], 'H37Rv': [60], 'as': [61], 'control.': [62], 'Results:No': [63], 'was': [65, 82, 92], 'isolates.': [70], 'In': [71], '75': [72], 'isolates,the': [76], 'rate': [78, 134], '96.': [83], '0%(72': [84], '/75),mainly': [85], 'region(94.': [88], '7%,71': [89], '/75).': [90], 'It': [91], 'found': [93], '15': [94], 'types': [95], 'mutations,including': [97], '12': [98], 'point': [99], 'mutations': [100], '3': [102, 155], 'combination': [103], 'mutations,involving': [104], '9': [105], 'sites': [106, 119], 'region': [109], '1': [111], 'site': [112], 'not(locus': [113], '569).': [114], 'The': [115], 'most': [116], 'frequent': [117], 'province': [127], 'codon531,codon526': [129], 'codon516,with': [131], 'total': [132], '84.': [136], '0%(63/75).': [137], 'Conclusion:The': [138], 'rapid': [139], 'method': [141], 'RFP': [143], 'drug': [144], 'resistance': [145], 'could': [150], 'be': [151], 'based': [152], 'on': [153], 'loci': [156]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2367824721', 'counts_by_year': [], 'updated_date': '2024-12-15T14:57:15.180995', 'created_date': '2016-06-24'}