Title: Study of correlation of diabetic nephropathy with serum endothelin(ET-1) and C-reactive protein (CRP)
Abstract: Objective To investigate the relationship of diabetic nephropathy with serum endothelin-1(ET-1) and C-reactive protein(CRP).Methods Levels of blood pressure,glucose,lipid,creatinine, ET-1,CRP and urinary albumin excretion(UAER) were measured and calculated in 86 patients with type 2 diabetes mellitus(T2DM) and 30 healthy subjects.Results Serum ET-1 and CRP were significantly higher in T2DM than in control(P0.05,P0.01).Serum ET-1 and CRP were increased with increment of serum creatinine and UAER (P 0.05,P 0.01).Conclusions Serum ET-1 and CRP may be involved in the development and progression of diabetic nephropathy.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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