Title: The Study of Serum Homocysteine and C-reactive Protein Levels in Acute Coronary Syndrome Patients with Impaired Glucose Tolerance
Abstract: Objective To investigate the change and relationship of serum homocysteine(HCY) and c-reactive protein(CRP) levels in acute coronary syndrome(ACS) patient with impaired glucose tolerance(IGT).Methods the levels of HCY and CRP in 89 ACS patients were determined.And the patients were divided into three groups by different glucose tolerance.They are NGT group,IGT group and T2DM group.Results ①Compared with NGT group the levels of HCY and CRP in ACS patients with IGT group and T2DM group were significantly higher.②Although the levels of HCY and CRP in T2DM group were higher than the IGT group,but have no statistically difference(P0.05).③The levels of HCY,CRP and HOMA-IR in ACS patients are closely related.Conclusion ①Inflammation in ACS patient with IGT and T2DM group is more notable than the NGT group.②Insulin resistance is a major factor lead to increase instability of atherosclerosis plaque.③Both HCY and CRP promote the process of ACS.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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