Title: Clinical Efficacy of Changyanning Capsule Combined with Mesalazine in the Treatment of Ulcerative Colitis
Abstract:Objective: To evaluate the clinical efficacy of Changyanning capsule combined with mesalazine in the treatment of ulcerative colitis. Methods: 89 patients with ulcerative colitis from January 2010 to ...Objective: To evaluate the clinical efficacy of Changyanning capsule combined with mesalazine in the treatment of ulcerative colitis. Methods: 89 patients with ulcerative colitis from January 2010 to September 2013 in our hospital were for the study,and they were randomly divided into a treatment group and a control group according to visiting sequence. 45 patients in the treatment group were given Changyanning capsules with mesalazine treatment,and in the control group 44 cases were given mesalazine treatment. Serum IL- 1,IL- 8,TNF- α,Fib,MPV and clinical outcomes in both groups were compared. Results: After treatment for 30 d,the serum IL- 1,IL- 8,TNF- α,Fib,MPV were significantly decreased in both groups( P 0. 05),but IL- 1,IL- 8,TNF- α,Fib,MPV in the treatment group were lower than those in the control group,and the differences were statistically significant( P 0. 05). In the treatment group the total effective rate was 95. 6%,which was higher than 81. 8% in the control group. Mann- Whitney U test showed that the clinical efficacy of the treatment group was superior to that in the control group( P 0. 05),and the incidence of adverse events in two groups had no significant difference( P 0. 05). Conclusion: The clinical efficacy of Changyanning capsule combined with mesalazine in the treatment of ulcerative colitis is better than single mesalazine,which is worthy of clinical application.Read More
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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Cited By Count: 1
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