Title: Observation of combined oral mesalazine enema for ulcerative colitis 120 Cases
Abstract:Objective To observe the combined oral mesalazine enema for ulcerative colitis.Methods Totally 240 patients with mild to moderate ulcerative colitis were randomly divided into two groups:treatment gro...Objective To observe the combined oral mesalazine enema for ulcerative colitis.Methods Totally 240 patients with mild to moderate ulcerative colitis were randomly divided into two groups:treatment group,120 patients to oral mesalazine,1.0g/time,3 times/d,while giving the mesalamine enema(Sa Fu enema,4g/60ml,when diluted with 100ml) 4g/100ml,1 times/night,retention enema,8 weeks as a course;The control group of 120 patients to oral sulfasalazine tablets(Alicylazosulfapyridine,SASP) 1.0g,4 times/d.Treatment for 8 weeks.Results After 8 weeks,the treatment group efficiency and total efficiency is better than the control group,the difference was statistically significant(P0.05);the incidence of adverse reactions of both groups,the treatment group occurred in 13 cases,incidence 10.8%,in the control group of 68 patients,the incidence of 56.7%,treatment group was significantly lower than the control group,the difference was statistically significant(P0.05) .Conclusions Mesalazine has good clinical efficacy in treatment of ulcerative colitis,and less adverse reactions.Read More
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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