Title: Monitoring and significance of CRP and PCT before and after treatment in neonates with bacteriotoxemia
Abstract: Objective:To explore the diagnostic value of serum procalcitonin and CRP in neonates with bacteriotoxemia before and after treatment.Methods:We collected serum from 60 neonates with bacteriotoxemia and 60 neonates without infection.Serum procalcitonin was determined by immunochromatography,CRP was measured with trubidimetric assay.Results:The levels of PCT and CRP in neonates with bacteriotoxemia were higher significantly than those in neonate without bacteriotoxemia(P0.01).After appropriate treatment by antibiotics,PCT and CRP decreased obviously compared with those in acute period(P0.01).in the meantime,we found the sensibility and specificity of PCT were 88.2% and 100% respectively,and the sensibility and specificity of CRP were 89.5% and 70.8% respectively.Conclusion:Serum procalcitonin and CRP could be used as a rapid diagnostic marker for neonates with bacteriotoxemia,and it can also evaluate infection for patients.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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