Title: A comparative study on aripiprazole and risperidone in the treatment of schizophrenic patients
Abstract: Objective:To compare the efficacy and safety of aripiprazole and risperidone in the treatment of schizophrenia.Methods:Seventy-seven patients with schizophrenia by CCMD-3 are randomly allocated to two groups treated with aripiprazole or risperidone respectively for 8 weeks.The Positive and Negative Syndrome Scale(PANS-S) and Treatment Emergent Side effect Scale(TESS) were used to e-valuate the efficacy and adverse effect respectively.Results: The efficacy rate of aripiprazole was 89.7%,in which 71.8% were improved markedly.The efficacy rate of risperdone was 86.8%,in which 71.1% were improved markedly.The PANSS scores in both groups no significantly after treatment for eight weeks(P0.05).The incidence of untoward reaction in aripiprazole group was lower than that in ris-perdone group and the difference was significant(P0.05).Conclusions: Both drugs are effective exactly in the treatment of schizophrenic patients and have fewer side effects.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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Cited By Count: 2
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