Title: Contrast-enhanced ultrasonography for evaluation of blunt hepatic trauma with active bleeding
Abstract: Objective To evaluate contrast-enhanced ultrasonography in diagnosis of blunt hepatic trauma with active bleeding.Methods Self-made miniature impactor was used to make models of blunt hepatic trauma in ten pigs.Conventional two-dimensional ultrasonography and contrast-enhanced ultrasonography were used to detect local echo changes of the livers before and instantly after impacting.After experiments the livers were taken out for pathologic examination.Hematoxylin and eosin staining were performed on injuried regions.Results The sonographic pattern of lesions in the pigs' livers at conventional ultrasonography was hypo-echoic in various degrees or anechoic against normal parenchyma with poorly-defined margins.The ruptures of liver capsules were observed in 7 pigs,whereas the capsule ruptures were not showed in the other 3 pigs.The different degrees of blood accumulation were found under the diaphragm in ten pigs.The radiate enhancement of vessels was interrupted in the lesion areas in arterial phase and portal phase was demonstrated with contrast-enhanced ultrasonography.The microbubbles flowed from the ruptures to the areas of blood accumulation.The enhancement of lesion area was more delayed than that of healthy parenchyma.During the delayed phase the enhanced echogenicity of the normal parenchyma began to weaken,whereas the echogenicity of lesions weakened slowly.The injuried areas were against to normal parenchyma with clear borders due to contrast agent.Gross pathologic findings demonstrated that acute blunt hepatic traumas and liver captures happened in 10 pigs.Gross pathologic findings were consistent with the contrast-enhanced ultrasonographic results.Conclusions Contrast-enhanced ultrasonography can observe blunt hepatic trauma with active bleeding in real time,which is valuable to further clinical treatment.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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Cited By Count: 2
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