Title: Gray-scale contrast-enhanced ultrasonography in diagnosis of acute piercing hepatic trauma of rats
Abstract: Objective To evaluate the value of gray-scale contrast-enhanced ultrasonography (CEUS) in diagnosis of acute piercing hepatic trauma of rats. Methods Forty piercing hepatic traumas were induced in 20 rats. Conventional ultrasonography and CEUS were performed to detect the position and degree of the traumatic lesions. The results of CEUS were compared with pathologic findings. Results Forty traumatic lesions were created successfully at different position in the rat`s livers. CEUS can clearly display the position and haematoma extent of hepatic traumas. Inactive haematoma in 27 hepatic lesions were demonstrated as anechoic defects in arterial phase, portal phase and late phase of CEUS. There was obvious demarcation between haematoma and normal liver parenchyma. And the microbubbles could be seen to flow from the ruptures to the areas of blood accumulation in 8 traumatic lesions with active bleeding through CEUS. The sensitivity of CEUS in detecting the traumatic lesion (87.5%,35/40) was significantly higher than that of conventional ultrasonography (20%,8/40) (P=0.000). Conclusion Gray-scale CEUS could remarkably improve the diagnostic level of conventional ultrasound and has clinical value in diagnosing hepatic trauma.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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