Title: Protective effects of xuebijing injection on ischemia -reperfusion injury of rat kidney
Abstract:Objective To investigate the effect of xuebijing injection on ischemia-reperfusion injury of rat kidney . Methods The rats were divided into three groups: sham operation group, renal ischemia -reperfu...Objective To investigate the effect of xuebijing injection on ischemia-reperfusion injury of rat kidney . Methods The rats were divided into three groups: sham operation group, renal ischemia -reperfusion group and xuebijing injection treated group. Serum maleic dialdehyde (MDA), superoxide dismutase (SOD), blood urea nitrogen (BUN), creatinine (Cr), and renal MDA, SOD were measured after 24 hrs reperfusion. Renal ultrastructure was observed. Results Compared with sham operation group, serum and renal MDA, SOD, blood BUN, Cr were significant different in renal ischemia-reperfusion group (t=-79.21,-12.27,-61.37,-39.37,-33.17,-16.11,P0.05) ; Compared with renal ischemia -reperfusion group, serum and renal MDA, SOD, blood BUN, Cr were significant different in xuebijing injection treated group (t=-41.52,-19.31,-58.31,-52.40,-12.39,4.07,P0.05). Detecting by transmission electron microscope, xuebijing injection relieved the renal ultrastructure injury significantly. Conclusion Xuebijing injection has protective effects on ischemia-reperfusion injury of rat kidney.Read More
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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