Title: Significance and expression of vascular endothelial growth factor and E-cadherin in non-small cell lung Carcinomas
Abstract: Objectives To study the expression of vascular endothelial growth factor (VEGF) and E cadherin (E cd) in non small cell lung carcinomas (NSCLC) and explore the mechanism of invasion and metastasis of tumor cell. Method The expression of VEGF and E cd was analyzed in surgical specimens (43 cases of NSCLC) by SP immunohistochemical method. Results The positive rates of VEGF in the case of good differentiation and poor middle differentiation were 60 0% and 86 9% respectively,and those of E cd were 65 0% and 34 9%. The expression of VEGF and E cd in the case of metastasis was significantly different from that in the case without metastasis. Conclusion The expression of VEGF and E cd is correlated well with invasion and metastasis of NSCLC.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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