Title: Clinical observation of randomized double-blind and multicenter trial on Qiliqiangxin capsule in the treatment of chronic heart failure
Abstract: ObjectiveTo observe the effect and safety of the Qiliqiangxin capsule in the treatment of chronic heart failure.MethodsUsing the parallel randomized,positive control,double-blind,double-simulation and multi-center clinical research method,488 patients with coronary disease,heart failure duo to hypertension were randomly divided into Qiliqiangxin capsule treatment group(326 cases) and Xinbao pill control group(162 cases),with a treatment course of 4 weeks for both groups.The heart function grading,Lee's scoring of heart failure,cardiac systolic and diastolic function,traditional Chinese medicine symdromes,quality of life and parameters of safety were observed.Results(1) The effective rates in treatment group and control group were 48.8% and 41.4% respectively,there was no significant difference in total effective rates(78.5% vs 71.6%) between the two groups(P0.05).(2) The effective rates of Lee's scoring in treatment group and control group were 42.3% and 32.1% respectively,and the total effective rates were 82.5% and 72.8% respectively,there was a significant difference between the two groups(P0.05 or P0.01).(3)The effective rates for traditional Chinese medicine syndromes in treatment group and control group were 46.6% and 32.1% respectively,and the total effective rates were 90.2% and 82.1% respectively,there was a significant difference between the two groups(P0.05 or P0.01).(4) The LVEF and E/A ratio in treatment group were obviously increased,and the cardiac systolic and diastolic function were improved.(5)The improvement of life quality in treatment group was obviously superior to that in control group.(6) No adverse effect was found in treatment group.ConclusionQiliqiangxin capsule has obvious curative effect and safety in the treatment of chronic heart failure.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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Cited By Count: 7
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