Title: The Study of Effective Anti-tumor Activity Parts on Apoptosis
Abstract: Objective To separate and select anti-tumor activity site of Ampelopsis japonica Mak,and explore its machine processed.Methods The anti-tumor activity of the different extracts and fractions were determined by MTT assay.The effects of active site on the apoptosis of HepG2 cells were studied by Hochest/PI staining.Results In the range of 25-200 mg/L,all of the ethylether and acetate position,fractions P2 and P3,strongly inhibited cell proliferation of HepG2,and the suppression ratio was raised with increasing concentrations of drug.Conclusion The ethylether and acetate positions are the effective anti-tumor parts from Ampelopsis japonica Mak,Which can kill and induce apoptosis of HepG2 cells.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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