Title: Antitumor activity of polysaccharides from angelica and astragalus in vitro
Abstract: The present study was carried out to evaluate antit umor activity of polysaccharides from angelica and astragalus (AAP )in vitro. Inhibition rate, percentage of viability and IC50 were served as target to evaluate its anti tumor activity on human tumor cell lines (Hela cell, HepG 2 cell, A549 cell, SPCA-1 cell and BGC-823 cell) in vitro through MTT method. The results showed that AAP exh ibited greater in vitro cytotoxicity on BGC-823 cel l and Hela cell than on HepG-2, A549, SPCA-1 cells. And the in hibition rates of 5-FU on BGC-823 cell had no a sig nificant difference from that of AAP at a concentration of 8 0 µg/mL. These results implied that AAP had an obvious antitumor activity in vitro.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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