Title: Antimicrobial activities of 26Yunnan plants extracts against clinical multi-drug resistant pathogens in vitro
Abstract: To determine the in vitro antimicrobial activities of 80%ethanol extracts from 26plants originated in southeast of Yunnan.The ethanol extracts of the collected plant samples were subjected to screen of the antibacterial and antifungal activity by the agar hole diffusion test.The minimum inhibitory concentration(MIC) and minimum bactericidal concentration(MBC) or minimum fungicidal concentration(MFC) were determined by serial dilution with a standard broth microdilution method.The results showed that 9of the 26extracts were active with different potency against strains of Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida albicans.The most active extracts against Staphylococcusa ureus and methicillin-resistant S.aureus(MRSA) were fromRhodoleiap arvipetala Tong,Diplopanax stachyanthus Hand.-Mazz,Sarcosperma kachinense Exell var.simondii Lam.et Royen,Coelogyne leucantha W.W.Smith and Sunipia bicolor.Their MICs /MBCs(mg /L) were 512 /2048-2048,512 /2048-2048,256-512 /2048-2048,512-1024 /1024-2048and 512-1024 /2048,respectively.Sladenia celastrifolia Kurz showed strong activity against P.aeruginosaand C.albicans,and the MICs /MBCs(MFCs) were 512-2048 /2048and 2048 /2048mg /L,respectively.All these plants showed weak inhibition against Escherichia coli.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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