Title: Effect of Human Umbilical Vein Endothelial Cells and PC - 3 Cells in Cell Cycle and Apoptosis Induced by Ionizing - irradiation
Abstract:Objective To preliminarily investigate the effect of various dose of radiation on Cell Cycle and apoptosis of primary human umbilical vein endothelial cells(HUVECs) and PC - 3 cells.Methods Morphology...Objective To preliminarily investigate the effect of various dose of radiation on Cell Cycle and apoptosis of primary human umbilical vein endothelial cells(HUVECs) and PC - 3 cells.Methods Morphology and flow cytometry(FCM)were used to detect changes of cell cycle and apoptosis in HUVECs and PC - 3 cells radiated with 6MV X - ray.Results At hour 24 or 48 after radiation,changes of cell cycle in HUVECs and PC - 3 cells were detected but no apoptosis was induced. Conclusion Radiation can induce retardation of cell cycle but no apoptosis in primay HUVECs and PC - 3 cells, it suggests that the two kinds of cells have part resistance against radiation.Read More
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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