Title: Clinical Research on Retention Enema of Traditional Chinese on Serum Levels of Inflammatory Factors of Ulcerative Colitis Patients
Abstract: Objective: To investigate Influence of retention enema of traditional Chinese medicine on serum levels of inflammatory factors of ulcerative colitis patients. Methods: 102 cases of ulcerative colitis patients were randomly divided into control group(n = 51) and observation group(n = 51). The control group was treated with Sulfasalazine,1. 5- 2. 0 g each time and 3 times a day. The observation group received retention enema of traditional Chinese medicine for 4 courses and 15 days as a course. Serum TNF-α and IL-6 levels were detected using double antibody sandwich enzyme linked immunosorbent assay(ELISA). Clinical symptoms such as abdominal pain,diarrhea,mucous stool with pus and blood,tenesmus signs of two groups were analyzed. Clinical curative effects of two groups were analyzed by colonoscopy. Results: Before treatment,there was no difference of serum TNF- alpha and IL-6 levels in two groups(P 0. 05). After treatment,serum TNF- and IL-6 levels of two groups decreased significantly compared with before treatment(P 0. 05).Serum TNF-α and IL-6 levels in the observation group decreased more significantly than that of the control group(P 0. 05). After treatment,Clinical symptoms in the two groups improved significantly(P 0. 05). And the observation group improved more significantly than the control group(P 0. 05). The total effective rate of the two groups was 84. 31% and 96. 08%. The total effective rate of observation group was higher than that of control group(P 0. 05). Conclusion: Retention enema of traditional Chinese medicine can significantly inhibit the levels of inflammatory factors in patients with ulcerative colitis and has significant clinical efficacy.
Publication Year: 2015
Publication Date: 2015-01-01
Language: en
Type: article
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