Title: Effect of Taurine and Guanidinoethane Sulfonate on Glutathione Metabolism in the Rat
Abstract: Taurine is synthesized via the oxidation and decarboxylation of cysteine (Cys), a precursor for glutathione (GSH) biosynthesis. GSH is the major intracellular nonprotein sulfhydryl compound and is important in various biochemical processes, including detoxification of reactive oxygen species and electrophilic metabolites formed from xenobiotics. It is known that dietary sulfur amino acids, such as Cys or methionine, significantly influence the synthesis of taurine9,27 and GSH9,29. However, the effect of dietary taurine on Cys or GSH metabolism has long been ignored.
Publication Year: 1998
Publication Date: 1998-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 2
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