Publication Information

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{'<h3>Purpose</h3>': [0], 'It': [1], 'has': [2], 'been': [3], 'found': [4], 'that': [5], 'Camk2d': [6, 43, 60, 75, 96, 148, 168, 178], '(calcium/calmodulin': [7], 'dependent': [8], 'protein': [9], 'kinase': [10], 'II': [11], 'delta)': [12], 'is': [13], 'related': [14], 'to': [15, 194], 'E-C': [16], 'couple': [17], 'and': [18, 21, 46, 67, 85, 99, 144, 152], 'myocardial': [19, 62, 132, 189], 'hypertrophy': [20], 'heart': [22], 'failure': [23], 'in': [24, 35, 44, 61, 172], 'pathological': [25], 'states.': [26], 'Moreover,': [27], 'its': [28], 'function': [29], 'alteration': [30], 'may': [31], 'play': [32], 'some': [33], 'role': [34], 'arrhythmia.': [36], 'To': [37], 'further': [38], 'investigate': [39], 'the': [40], 'mechanism': [41], 'of': [42, 48, 167, 177], 'onset': [45], 'development': [47], 'arrhythmia,': [49], 'we': [50], 'have': [51], 'built': [52], 'a': [53], 'platform': [54], 'for': [55, 146], 'next': [56], 'stage': [57], 'by': [58, 64, 70, 79, 110, 150, 158, 180], 'overexpressing': [59], 'cells': [63, 133, 156, 190, 196], 'lentivirus': [65, 83, 89, 128, 143, 160], 'transduction': [66], 'inhibiting': [68], 'it': [69], 'RNAi.': [71], 'Method': [72], '(1)': [73], 'Rat': [74], 'ORF': [76], 'was': [77, 107, 125], 'cloned': [78], 'PCR,': [80], 'ligated': [81], 'into': [82, 88, 127], 'vector': [84], 'then': [86, 108], 'packaged': [87, 126], 'particles.': [90, 129], '(2)': [91], '3': [92], 'shRNA': [93], 'sequences': [94], 'against': [95], 'were': [97, 137], 'designed': [98], 'cloned.': [100], 'The': [101, 121], 'one': [102], 'with': [103, 113, 139, 191, 197], 'highest': [104], 'inference': [105], 'efficiency': [106], 'screened': [109], 'westernblot': [111], 'following': [112], 'calcium': [114], 'phosphate': [115], 'transfection': [116], 'on': [117], '293': [118], 'cells.': [119], '(3)': [120], 'selected': [122], 'RNAi': [123, 142, 173], 'clone': [124], '(4)': [130], 'Cultured': [131], 'from': [134], 'neonatal': [135], 'rats': [136], 'transducted': [138, 157], 'overexpression': [140, 159], 'or': [141, 201], 'harvested': [145], 'analysing': [147], 'level': [149, 166], 'Realtime-PCR': [151], 'westernblot.': [153], '<h3>Result</h3>': [154], 'Myocardial': [155], 'exhibited': [161], 'an': [162], 'over': [163], '5-time': [164], 'higher': [165], 'than': [169], 'normal,': [170], 'while': [171], 'transfected': [174], 'cells,': [175], 'expression': [176], 'decreased': [179], 'around': [181], '50%.': [182], '<h3>Conclusion</h3>': [183], 'Lentivirus': [184], 'can': [185], 'efficiently': [186], 'transduct': [187], 'primary': [188], 'exogenous': [192], 'genes': [193], 'obtain': [195], 'special': [198], 'gene': [199], 'up-': [200], 'down-regulated.': [202]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2069799681', 'counts_by_year': [], 'updated_date': '2024-12-12T08:17:55.698735', 'created_date': '2016-06-24'}