<i>Plasmodium falciparum</i>in Owl Monkeys: Drug Resistance and Chloroquine Binding Capacity

Name: Work Video:
Duration: 3 min 30 s
Description: Erythrocytes infected with chloroquine-sensitive Plasmodium falciparum bind chloroquine with an apparent intrinsic association constant of 1.5 x 10(7) liters per mole. Such high-affinity binding of chloroquine is absent or deficient in uninfected erythrocytes and in erythrocytes infected with chloroquine-resistant Plasmodium falciparum.
Coy D. Fitch
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