Publication Information

{'id': 'https://openalex.org/W2054262691', 'doi': 'https://doi.org/10.1016/s0140-6736(84)92328-6', 'title': 'BM 13.177, A SELECTIVE BLOCKER OF PLATELET AND VESSEL WALL THROMBOXANE RECEPTORS, IS ACTIVE IN MAN', 'display_name': 'BM 13.177, A SELECTIVE BLOCKER OF PLATELET AND VESSEL WALL THROMBOXANE RECEPTORS, IS ACTIVE IN MAN', 'publication_year': 1984, 'publication_date': '1984-05-01', 'ids': {'openalex': 'https://openalex.org/W2054262691', 'doi': 'https://doi.org/10.1016/s0140-6736(84)92328-6', 'mag': '2054262691', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/6143969'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0140-6736(84)92328-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S49861241', 'display_name': 'The Lancet', 'issn_l': '0140-6736', 'issn': ['0140-6736', '1474-547X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5003292078', 'display_name': 'Paolo Gresele', 'orcid': 'https://orcid.org/0000-0001-5365-8445'}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Paolo Gresele', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069352573', 'display_name': 'Jef Arnout', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Jef Arnout', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103705371', 'display_name': 'W. J. Janssens', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Walter Janssens', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022448402', 'display_name': 'Hans Deckmyn', 'orcid': 'https://orcid.org/0000-0003-3952-5501'}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Hans Deckmyn', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032406936', 'display_name': 'Jan Lemmens', 'orcid': 'https://orcid.org/0000-0001-6069-8891'}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Jan Lemmens', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111899557', 'display_name': 'Jos Vermylen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Jos Vermylen', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research Department of Medical Research University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 6830, 'currency': 'USD', 'value_usd': 6830, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 10.231, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 75, 'citation_normalized_percentile': {'value': 0.872147, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '323', 'issue': '8384', 'first_page': '991', 'last_page': '994'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10678', 'display_name': 'Inflammatory mediators and NSAID effects', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10678', 'display_name': 'Inflammatory mediators and NSAID effects', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12539', 'display_name': 'Pharmacology and Obesity Treatment', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thromboxane-a-synthase', 'display_name': 'Thromboxane-A synthase', 'score': 0.64332557}, {'id': 'https://openalex.org/keywords/thromboxane-receptor', 'display_name': 'Thromboxane receptor', 'score': 0.6359463}, {'id': 'https://openalex.org/keywords/thromboxane-b2', 'display_name': 'Thromboxane B2', 'score': 0.45119947}], 'concepts': [{'id': 'https://openalex.org/C2781024287', 'wikidata': 'https://www.wikidata.org/wiki/Q774909', 'display_name': 'Thromboxane A2', 'level': 3, 'score': 0.81120646}, {'id': 'https://openalex.org/C89560881', 'wikidata': 'https://www.wikidata.org/wiki/Q101026', 'display_name': 'Platelet', 'level': 2, 'score': 0.7717662}, {'id': 'https://openalex.org/C2776785769', 'wikidata': 'https://www.wikidata.org/wiki/Q412212', 'display_name': 'Thromboxane', 'level': 3, 'score': 0.70300174}, {'id': 'https://openalex.org/C173202427', 'wikidata': 'https://www.wikidata.org/wiki/Q408575', 'display_name': 'Thromboxane-A synthase', 'level': 4, 'score': 0.64332557}, {'id': 'https://openalex.org/C51603380', 'wikidata': 'https://www.wikidata.org/wiki/Q411978', 'display_name': 'Thromboxane receptor', 'level': 4, 'score': 0.6359463}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.59933263}, {'id': 'https://openalex.org/C2778078955', 'wikidata': 'https://www.wikidata.org/wiki/Q407699', 'display_name': 'Arachidonic acid', 'level': 3, 'score': 0.5911771}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.56816286}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.542428}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.53881663}, {'id': 'https://openalex.org/C2781080829', 'wikidata': 'https://www.wikidata.org/wiki/Q3009646', 'display_name': 'Thromboxane B2', 'level': 3, 'score': 0.45119947}, {'id': 'https://openalex.org/C163415756', 'wikidata': 'https://www.wikidata.org/wiki/Q126473', 'display_name': 'Contraction (grammar)', 'level': 2, 'score': 0.42530218}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3487333}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.34699583}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.32069832}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.044606447}], 'mesh': [{'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D001808', 'descriptor_name': 'Blood Vessels', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011956', 'descriptor_name': 'Receptors, Cell Surface', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D011982', 'descriptor_name': 'Receptors, Prostaglandin', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D019796', 'descriptor_name': '15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001808', 'descriptor_name': 'Blood Vessels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001808', 'descriptor_name': 'Blood Vessels', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010974', 'descriptor_name': 'Platelet Aggregation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010974', 'descriptor_name': 'Platelet Aggregation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011449', 'descriptor_name': 'Prostaglandin Endoperoxides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011449', 'descriptor_name': 'Prostaglandin Endoperoxides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011450', 'descriptor_name': 'Prostaglandin Endoperoxides, Synthetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011450', 'descriptor_name': 'Prostaglandin Endoperoxides, Synthetic', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011897', 'descriptor_name': 'Random Allocation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011956', 'descriptor_name': 'Receptors, Cell Surface', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011982', 'descriptor_name': 'Receptors, Prostaglandin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017482', 'descriptor_name': 'Receptors, Thromboxane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D014661', 'descriptor_name': 'Vasoconstriction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014661', 'descriptor_name': 'Vasoconstriction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0140-6736(84)92328-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S49861241', 'display_name': 'The Lancet', 'issn_l': '0140-6736', 'issn': ['0140-6736', '1474-547X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/6143969', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W104407421', 'https://openalex.org/W1963860018', 'https://openalex.org/W1968374585', 'https://openalex.org/W1970777502', 'https://openalex.org/W1974319495', 'https://openalex.org/W1974351539', 'https://openalex.org/W1978420200', 'https://openalex.org/W1979833158', 'https://openalex.org/W1993210005', 'https://openalex.org/W2008839219', 'https://openalex.org/W2020066385', 'https://openalex.org/W2027591242', 'https://openalex.org/W2030087792', 'https://openalex.org/W2039176543', 'https://openalex.org/W2039330939', 'https://openalex.org/W2044880765', 'https://openalex.org/W2046921348', 'https://openalex.org/W2055693070', 'https://openalex.org/W2058984603', 'https://openalex.org/W2063990138', 'https://openalex.org/W2083789673', 'https://openalex.org/W2155027494', 'https://openalex.org/W2157121433', 'https://openalex.org/W2235018908', 'https://openalex.org/W2340410345', 'https://openalex.org/W2342443721', 'https://openalex.org/W2410591854', 'https://openalex.org/W2413698221'], 'related_works': ['https://openalex.org/W98406121', 'https://openalex.org/W4238761545', 'https://openalex.org/W2470326181', 'https://openalex.org/W2399782909', 'https://openalex.org/W2312229444', 'https://openalex.org/W2053182919', 'https://openalex.org/W2047854358', 'https://openalex.org/W2029344288', 'https://openalex.org/W2010146877', 'https://openalex.org/W1966682207'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2054262691', 'counts_by_year': [], 'updated_date': '2024-12-13T00:33:03.455000', 'created_date': '2016-06-24'}