Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2047854358', 'doi': 'https://doi.org/10.1016/0165-6147(91)90533-x', 'title': 'Thromboxane synthase inhibitors, thromboxane receptor antagonists and dual blockers in thrombotic disorders', 'display_name': 'Thromboxane synthase inhibitors, thromboxane receptor antagonists and dual blockers in thrombotic disorders', 'publication_year': 1991, 'publication_date': '1991-01-01', 'ids': {'openalex': 'https://openalex.org/W2047854358', 'doi': 'https://doi.org/10.1016/0165-6147(91)90533-x', 'mag': '2047854358', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1829559'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0165-6147(91)90533-x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31167473', 'display_name': 'Trends in Pharmacological Sciences', 'issn_l': '0165-6147', 'issn': ['0165-6147', '1873-3735'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5003292078', 'display_name': 'Paolo Gresele', 'orcid': 'https://orcid.org/0000-0001-5365-8445'}, 'institutions': [{'id': 'https://openalex.org/I27483092', 'display_name': 'University of Perugia', 'ror': 'https://ror.org/00x27da85', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I27483092']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Paolo Gresele', 'raw_affiliation_strings': ['Istituto di Semeiotica Medica, University of Perugia, Via Enrico dal Pozzo, I-06100, Italy'], 'affiliations': [{'raw_affiliation_string': 'Istituto di Semeiotica Medica, University of Perugia, Via Enrico dal Pozzo, I-06100, Italy', 'institution_ids': ['https://openalex.org/I27483092']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022448402', 'display_name': 'Hans Deckmyn', 'orcid': 'https://orcid.org/0000-0003-3952-5501'}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Hans Deckmyn', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research, University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research, University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003250364', 'display_name': 'Giuseppe G. Nenci', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I27483092', 'display_name': 'University of Perugia', 'ror': 'https://ror.org/00x27da85', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I27483092']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Giuseppe G. Nenci', 'raw_affiliation_strings': ['Istituto di Semeiotica Medica, University of Perugia, Via Enrico dal Pozzo, I-06100, Italy'], 'affiliations': [{'raw_affiliation_string': 'Istituto di Semeiotica Medica, University of Perugia, Via Enrico dal Pozzo, I-06100, Italy', 'institution_ids': ['https://openalex.org/I27483092']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111899557', 'display_name': 'Jos Vermylen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Jos Vermylen', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research, University of Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research, University of Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 6830, 'currency': 'USD', 'value_usd': 6830, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.775, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 123, 'citation_normalized_percentile': {'value': 0.849807, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '12', 'issue': None, 'first_page': '158', 'last_page': '163'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10678', 'display_name': 'Inflammatory mediators and NSAID effects', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13489', 'display_name': 'Synthesis of β-Lactam Compounds', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thromboxane-a-synthase', 'display_name': 'Thromboxane-A synthase', 'score': 0.9381404}, {'id': 'https://openalex.org/keywords/thromboxane-receptor', 'display_name': 'Thromboxane receptor', 'score': 0.8272283}, {'id': 'https://openalex.org/keywords/prostaglandin-h2', 'display_name': 'Prostaglandin H2', 'score': 0.65029985}], 'concepts': [{'id': 'https://openalex.org/C173202427', 'wikidata': 'https://www.wikidata.org/wiki/Q408575', 'display_name': 'Thromboxane-A synthase', 'level': 4, 'score': 0.9381404}, {'id': 'https://openalex.org/C2781024287', 'wikidata': 'https://www.wikidata.org/wiki/Q774909', 'display_name': 'Thromboxane A2', 'level': 3, 'score': 0.858637}, {'id': 'https://openalex.org/C51603380', 'wikidata': 'https://www.wikidata.org/wiki/Q411978', 'display_name': 'Thromboxane receptor', 'level': 4, 'score': 0.8272283}, {'id': 'https://openalex.org/C2776785769', 'wikidata': 'https://www.wikidata.org/wiki/Q412212', 'display_name': 'Thromboxane', 'level': 3, 'score': 0.7115705}, {'id': 'https://openalex.org/C89560881', 'wikidata': 'https://www.wikidata.org/wiki/Q101026', 'display_name': 'Platelet', 'level': 2, 'score': 0.672459}, {'id': 'https://openalex.org/C2780978440', 'wikidata': 'https://www.wikidata.org/wiki/Q416567', 'display_name': 'Prostaglandin H2', 'level': 4, 'score': 0.65029985}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.6172968}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.50403136}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.5006497}, {'id': 'https://openalex.org/C3018697912', 'wikidata': 'https://www.wikidata.org/wiki/Q179217', 'display_name': 'Platelet activation', 'level': 3, 'score': 0.4971967}, {'id': 'https://openalex.org/C2778122271', 'wikidata': 'https://www.wikidata.org/wiki/Q410943', 'display_name': 'Receptor antagonist', 'level': 4, 'score': 0.4650736}, {'id': 'https://openalex.org/C2776885963', 'wikidata': 'https://www.wikidata.org/wiki/Q245204', 'display_name': 'Antagonist', 'level': 3, 'score': 0.3954645}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3472647}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.2607772}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.18295851}], 'mesh': [{'descriptor_ui': 'D011982', 'descriptor_name': 'Receptors, Prostaglandin', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D013927', 'descriptor_name': 'Thrombosis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D013930', 'descriptor_name': 'Thromboxane-A Synthase', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011982', 'descriptor_name': 'Receptors, Prostaglandin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017482', 'descriptor_name': 'Receptors, Thromboxane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013927', 'descriptor_name': 'Thrombosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013930', 'descriptor_name': 'Thromboxane-A Synthase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0165-6147(91)90533-x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31167473', 'display_name': 'Trends in Pharmacological Sciences', 'issn_l': '0165-6147', 'issn': ['0165-6147', '1873-3735'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1829559', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.58, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 37, 'referenced_works': ['https://openalex.org/W107715711', 'https://openalex.org/W149875176', 'https://openalex.org/W1562882205', 'https://openalex.org/W1597162209', 'https://openalex.org/W1604451973', 'https://openalex.org/W1945490092', 'https://openalex.org/W1966120720', 'https://openalex.org/W1966682207', 'https://openalex.org/W1970095573', 'https://openalex.org/W1978420200', 'https://openalex.org/W1984619903', 'https://openalex.org/W1989210738', 'https://openalex.org/W1993210005', 'https://openalex.org/W2008839219', 'https://openalex.org/W2034543055', 'https://openalex.org/W2041050563', 'https://openalex.org/W2047830083', 'https://openalex.org/W2049728749', 'https://openalex.org/W2054262691', 'https://openalex.org/W2055693070', 'https://openalex.org/W2070963167', 'https://openalex.org/W2077459776', 'https://openalex.org/W2081891738', 'https://openalex.org/W2086270576', 'https://openalex.org/W2104380573', 'https://openalex.org/W2117694083', 'https://openalex.org/W2156598056', 'https://openalex.org/W2336547811', 'https://openalex.org/W2404343508', 'https://openalex.org/W2406272096', 'https://openalex.org/W2412060844', 'https://openalex.org/W2417667988', 'https://openalex.org/W2460490661', 'https://openalex.org/W2521108256', 'https://openalex.org/W4244537139', 'https://openalex.org/W4252241269', 'https://openalex.org/W4252703427'], 'related_works': ['https://openalex.org/W2399782909', 'https://openalex.org/W2312229444', 'https://openalex.org/W2085760669', 'https://openalex.org/W2072722254', 'https://openalex.org/W2047854358', 'https://openalex.org/W2045421996', 'https://openalex.org/W2029344288', 'https://openalex.org/W1994245012', 'https://openalex.org/W1967177765', 'https://openalex.org/W106635558'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2047854358', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-12T17:16:46.379879', 'created_date': '2016-06-24'}