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'target': [73, 187], 'inhibition.': [74], 'As': [75], 'proof': [77, 174], 'concept,': [79], 'we': [80, 151], 'knockdown': [82, 127, 189], 'firefly': [85, 166], 'luciferase': [86, 117], 'reporter': [87], 'U1i,': [95], 'evaluated': [97], 'inhibitory': [99], 'potential': [100], 'both': [101], 'vitro': [103], 'vivo.': [106, 191], 'Co-transfection': [107], 'constructs': [112, 132, 164], 'showed': [113], 'additive': [114], 'reduction': [115], 'expression': [118], 'up': [119], 'to': [120, 185], '95%': [121], 'vitro.': [123], 'attained': [125], 'similar': [126], 'when': [128], 'were': [133], 'hydrodynamically': [134], 'transfected': [135], 'into': [136], 'murine': [137, 160], 'liver,': [138], 'demonstrating': [139], 'first': [142], 'time': [143], 'successful': [144], 'vivo': [146], 'application': [147], 'U1i.': [149], 'Moreover,': [150], 'demonstrated': [152], 'long-term': [153], 'silencing': [155], 'AAV-mediated': [157], 'transduction': [158], 'muscle': [161], 'with': [162], 'RNAi/U1i': 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