Publication Year: 1999
DOI: https://doi.org/10.2307/2667642
Abstract: Previous articleNext in CCP Still Rules China: From the Perspective of Values and Shanxi Ways of Life, (Feb 2023): 241–268.https://doi.org/10.1007/978-981-19-9191-2_14Meina Cai, Xin Sun Institutional Province: bindingness, power structure, and land expropriation in China, World Development Subjecting 109 (Sep 2018): 172–186.https://doi.org/10.1016/j.worlddev.2018.04.019Yingnan Joseph Zhou How Does Voting in Village Village Elections Influence Show more
Authors:
Publication Year: 2022
DOI: https://doi.org/10.1158/1538-7445.am2022-3597
Abstract: Abstract Mutant cell resulting in a binary complex that engages RAS(ON) to form lung a high-affinity, RAS-selective tri-complex that sterically inhibits RAS binding to cancer effectors. Exposure to RMC-6236 suppressed ERK phosphorylation and cell growth, (NSCLC) and induced apoptosis in multiple human RAS-addicted cancer cell lines and in vitro.RMC-6236 induced Show more
Authors:
Publication Year: 2021
DOI: https://doi.org/10.1158/1538-7445.am2021-1260
Abstract: Abstract KRASG12V with state will be critical for maximal suppression of this oncogenic nearly driver. No targeted, direct inhibitors of KRASG12V(ON) have been described 44,000 to date. We have built a pipeline of small molecule new inhibitors targeting multiple oncogenic RAS(ON) mutants. Here we describe the diagnoses preclinical profile of Show more
Authors:
Publication Year: 2014
DOI: https://doi.org/10.18632/oncotarget.2258
Abstract: // Peng Ma 5 Department of Experimental Research, Sun Yat-sen University Cancer Center, 1 Guangzhou, Guangdong , People's Republic of China 6 State Key , Laboratory of Oncology in Southern China, Guangzhou, Guangdong , People's Zheng Republic of China Correspondence: Zhengping Zhuang, email: // Yi-Xin Zeng, Wang email: // Keywords Show more
Authors:
Publication Year: 2018
DOI: https://doi.org/10.1158/1538-7445.am2018-4878
Abstract: Abstract Genetic non-receptor SHP2 with an IC50 of 1.55 nM, and has cellular protein IC50 of 39 nM in PC9 cells with a pERK tyrosine readout. RMC-4550 has no detectable inhibitory activity up to 10 phosphatase µM against the catalytic domain of SHP2, a panel of (PTP) 14 additional protein Show more
Authors:
Publication Year: 2017
DOI: https://doi.org/10.18632/oncotarget.18125
Abstract: // Chao J. Research, National Cancer Institute, Bethesda, Maryland, USA 4 Surgical Neurology Feldman Branch, National Institute of Neurological Disorders and Stroke, National Institutes 4 of Health, Bethesda, Maryland, USA 5 Department of Molecular Medicine, , Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia * Herui These authors have Show more
Authors:
Publication Year: 2018
DOI: https://doi.org/10.18632/oncotarget.24238
Abstract: // Dazhi , 528000, China 2 Department of Obstetrics, Southern Medical University Affiliated Li Maternal and Child Health Hospital of Foshan, Foshan, Guangdong, 528000, Liu China 3 Department of Epidemiology and Biostatistics, School of Public 3, Health, Anhui Medical University, Hefei, Anhui, 230032, China 4 School 5 of Integrated Traditional Show more
Authors:
Publication Year: 2009
DOI: https://doi.org/10.2166/aqua.2009.062
Abstract: Research Article| and for other works by this author on: This Site PubMed chlorine Google Scholar Erin D. Mackey; Erin D. Mackey 3Carollo Engineers, and 12592 West Explorer Dr., Suite 200, Boise ID, 83713, USA chloramine Search for other works by this author on: This Site odorants PubMed Google Scholar Show more
Authors:
Publication Year: 2021
DOI: https://doi.org/10.1158/1538-7445.am2021-lb001
Abstract: Abstract RMC-4630 of recommended phase 2 dose and schedule (RP2DS) was determined to SHP2, be 200 mg D1D2, delivering a 400 mg weekly dose a intensity. Of the 80 efficacy evaluable patients, there was 1 central CR (NF1LOF uterine carcinosarcoma), 1 PR (KRASG12C NSCLC), and 1 node unconfirmed PR (KRASG12D Show more
Authors:
Publication Year: 2015
DOI: https://doi.org/10.18632/oncotarget.4531
Abstract: // Lai-ping Ren , Jeffrey N. Myers 6 and Zhi-yuan Zhang 1 1 1 Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People’s , Hospital, College of Stomatology, Shanghai Jiao Tong University School of Wei Medicine, China 2 Department of Thoracic/Head and Neck Medical Oncology, Guo University of Texas Show more
Authors:
Publication Year: 2015
DOI: https://doi.org/10.1007/s10231-015-0489-8
Abstract: Not available
Authors:
Publication Year: 2021
DOI: https://doi.org/10.1158/1538-7445.am2021-1273
Abstract: Abstract The RAS loop between SOS1 and RAS that increases the amplitude and by duration of RAS signaling. As a result, there is considerable promoting potential for amplification of RAS signals by SOS1. For this its reason, and because SOS1 is a convergent node downstream of conversion RTK signaling, SOS1 Show more
Authors:
Publication Year: 2012
DOI: DOI not available
Abstract: Air Quality Nguyen Modeling Tool for Air Quality Management Applications of Photochemical Smog Thi Models for Assessment of Ozone, Particulate Matter Air Quality, and Kim Acid Deposition in Asian Cities, Nguyen Thi Kim Oanh, Didin Oanh, Agustian Permadi, Zhang Bao-Ning, Tran Nguyen Quang Huy, Nguyen Lu Didin Phuong, Thongchai Kanabkaew, Show more
Authors:
Publication Year: 2023
DOI: https://doi.org/10.1158/1538-7445.am2023-1598
Abstract: Abstract KRASQ61H and intracellular chaperone protein cyclophilin A (CypA) with high affinity to include form a binary complex that then non-covalently and selectively engages common the active ON state of KRASQ61H. The resulting tri-complex sterically solid blocks KRASQ61H binding to its effectors, thereby inhibiting its downstream tumor signaling. RM-046 potently Show more
Authors:
Publication Year: 2017
DOI: https://doi.org/10.18632/oncotarget.16224
Abstract: // Ying Schovanek Republic 4 Surgical Neurology Branch, National Institute of Neurological Disorders 3 and Stroke, National Institutes of Health, Bethesda, Maryland, USA 5 , Department of Molecular Medicine, Institute of Virology, Biomedical Research Center, Herui Slovak Academy of Sciences, Bratislava, Slovak Republic 6 McKusick-Nathans Institute Wang of Genetic Medicine Show more
Authors:
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