Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4362581199', 'doi': 'https://doi.org/10.3389/fgene.2023.1152470', 'title': 'Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review', 'display_name': 'Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review', 'publication_year': 2023, 'publication_date': '2023-04-03', 'ids': {'openalex': 'https://openalex.org/W4362581199', 'doi': 'https://doi.org/10.3389/fgene.2023.1152470', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/37077538'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fgene.2023.1152470', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fgene.2023.1152470/pdf', 'source': {'id': 'https://openalex.org/S2597340651', 'display_name': 'Frontiers in Genetics', 'issn_l': '1664-8021', 'issn': ['1664-8021'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fgene.2023.1152470/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5045487040', 'display_name': 'Gianna Di Sario', 'orcid': 'https://orcid.org/0000-0003-1919-6050'}, 'institutions': [{'id': 'https://openalex.org/I4387155925', 'display_name': 'Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele', 'ror': 'https://ror.org/006x48140', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4387155925']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Gianna Di Sario', 'raw_affiliation_strings': ['Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I4387155925', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086637745', 'display_name': 'Valeria Rossella', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4387155925', 'display_name': 'Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele', 'ror': 'https://ror.org/006x48140', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4387155925']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Valeria Rossella', 'raw_affiliation_strings': ['Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I4387155925', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064741244', 'display_name': 'Elvira Smeralda Famulari', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4387155925', 'display_name': 'Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele', 'ror': 'https://ror.org/006x48140', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4387155925']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Elvira Smeralda Famulari', 'raw_affiliation_strings': ['Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I4387155925', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043628236', 'display_name': 'Aurora Maurizio', 'orcid': 'https://orcid.org/0000-0002-7194-4637'}, 'institutions': [{'id': 'https://openalex.org/I4387155925', 'display_name': 'Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele', 'ror': 'https://ror.org/006x48140', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4387155925']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Aurora Maurizio', 'raw_affiliation_strings': ['Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I4387155925', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052548980', 'display_name': 'Dejan Lazarević', 'orcid': 'https://orcid.org/0000-0003-4527-290X'}, 'institutions': [{'id': 'https://openalex.org/I4387155925', 'display_name': 'Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele', 'ror': 'https://ror.org/006x48140', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4387155925']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Dejan Lazarevic', 'raw_affiliation_strings': ['Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I4387155925', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059346148', 'display_name': 'Francesca Giannese', 'orcid': 'https://orcid.org/0000-0001-8695-649X'}, 'institutions': [{'id': 'https://openalex.org/I4387155925', 'display_name': 'Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele', 'ror': 'https://ror.org/006x48140', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4387155925']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Francesca Giannese', 'raw_affiliation_strings': ['Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I4387155925', 'https://openalex.org/I4210153126']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5042885679', 'display_name': 'Claudia Felici', 'orcid': 'https://orcid.org/0000-0002-1975-8378'}, 'institutions': [{'id': 'https://openalex.org/I4387155925', 'display_name': 'Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele', 'ror': 'https://ror.org/006x48140', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4387155925']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Claudia Felici', 'raw_affiliation_strings': ['Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centre for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy', 'institution_ids': ['https://openalex.org/I4387155925', 'https://openalex.org/I4210153126']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'apc_paid': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'fwci': 2.083, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 20, 'citation_normalized_percentile': {'value': 0.998554, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '14', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11287', 'display_name': 'Cancer Genomics and Diagnostics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11287', 'display_name': 'Cancer Genomics and Diagnostics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11289', 'display_name': 'Single-cell and spatial transcriptomics', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10449', 'display_name': 'Renal cell carcinoma treatment', 'score': 0.9934, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/liquid-biopsy', 'display_name': 'Liquid biopsy', 'score': 0.7871653}, {'id': 'https://openalex.org/keywords/omics', 'display_name': 'Omics', 'score': 0.4185695}], 'concepts': [{'id': 'https://openalex.org/C2779529041', 'wikidata': 'https://www.wikidata.org/wiki/Q22349364', 'display_name': 'Liquid biopsy', 'level': 3, 'score': 0.7871653}, {'id': 'https://openalex.org/C2775934546', 'wikidata': 'https://www.wikidata.org/wiki/Q179991', 'display_name': 'Biopsy', 'level': 2, 'score': 0.46539816}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.45446295}, {'id': 'https://openalex.org/C157585117', 'wikidata': 'https://www.wikidata.org/wiki/Q158666', 'display_name': 'Omics', 'level': 2, 'score': 0.4185695}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.4150996}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.4057226}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.40276554}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.39369982}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.37995362}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.29643703}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.27420428}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.100336164}], 'mesh': [], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fgene.2023.1152470', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fgene.2023.1152470/pdf', 'source': {'id': 'https://openalex.org/S2597340651', 'display_name': 'Frontiers in Genetics', 'issn_l': '1664-8021', 'issn': ['1664-8021'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109350', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/37077538', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fgene.2023.1152470', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fgene.2023.1152470/pdf', 'source': {'id': 'https://openalex.org/S2597340651', 'display_name': 'Frontiers in Genetics', 'issn_l': '1664-8021', 'issn': ['1664-8021'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.53, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 341, 'referenced_works': ['https://openalex.org/W144423133', 'https://openalex.org/W1500925570', 'https://openalex.org/W1518170435', 'https://openalex.org/W1540722338', 'https://openalex.org/W1593758286', 'https://openalex.org/W1601681275', 'https://openalex.org/W1620079123', 'https://openalex.org/W1647369727', 'https://openalex.org/W1701091641', 'https://openalex.org/W1851952311', 'https://openalex.org/W1906566368', 'https://openalex.org/W1917588793', 'https://openalex.org/W1921594208', 'https://openalex.org/W1940682904', 'https://openalex.org/W1950118853', 'https://openalex.org/W1968762427', 'https://openalex.org/W1969720359', 'https://openalex.org/W1977184198', 'https://openalex.org/W1980075462', 'https://openalex.org/W1983466841', 'https://openalex.org/W1984731778', 'https://openalex.org/W1989410892', 'https://openalex.org/W1989457196', 'https://openalex.org/W1991472738', 'https://openalex.org/W1995405710', 'https://openalex.org/W2000056288', 'https://openalex.org/W2003097348', 'https://openalex.org/W2006288875', 'https://openalex.org/W2008245736', 'https://openalex.org/W2010043146', 'https://openalex.org/W2017650189', 'https://openalex.org/W2019552331', 'https://openalex.org/W2021459974', 'https://openalex.org/W2022616393', 'https://openalex.org/W2030072422', 'https://openalex.org/W2040257851', 'https://openalex.org/W2040928840', 'https://openalex.org/W2042194227', 'https://openalex.org/W2050574264', 'https://openalex.org/W2051974123', 'https://openalex.org/W2053309035', 'https://openalex.org/W2061891352', 'https://openalex.org/W2062408118', 'https://openalex.org/W2064977507', 'https://openalex.org/W2069089843', 'https://openalex.org/W2069594922', 'https://openalex.org/W2077248943', 'https://openalex.org/W2078424563', 'https://openalex.org/W2082784086', 'https://openalex.org/W2088942535', 'https://openalex.org/W2089135124', 'https://openalex.org/W2089370460', 'https://openalex.org/W2090461073', 'https://openalex.org/W2099828433', 'https://openalex.org/W2102322990', 'https://openalex.org/W2102576865', 'https://openalex.org/W2103890313', 'https://openalex.org/W2106340111', 'https://openalex.org/W2106619117', 'https://openalex.org/W2110154511', 'https://openalex.org/W2111465765', 'https://openalex.org/W2111976640', 'https://openalex.org/W2115093090', 'https://openalex.org/W2119204950', 'https://openalex.org/W2120869188', 'https://openalex.org/W2121743948', 'https://openalex.org/W2123629153', 'https://openalex.org/W2126236874', 'https://openalex.org/W2126816979', 'https://openalex.org/W2128227827', 'https://openalex.org/W2128891846', 'https://openalex.org/W2129833022', 'https://openalex.org/W2130979840', 'https://openalex.org/W2139799027', 'https://openalex.org/W2139838862', 'https://openalex.org/W2146157095', 'https://openalex.org/W2153733592', 'https://openalex.org/W2157820287', 'https://openalex.org/W2161862739', 'https://openalex.org/W2161863487', 'https://openalex.org/W2162150195', 'https://openalex.org/W2163567255', 'https://openalex.org/W2165786425', 'https://openalex.org/W2171237493', 'https://openalex.org/W2171892226', 'https://openalex.org/W2173818354', 'https://openalex.org/W2239118478', 'https://openalex.org/W2253972942', 'https://openalex.org/W2269331124', 'https://openalex.org/W2276975311', 'https://openalex.org/W2280092090', 'https://openalex.org/W2294228192', 'https://openalex.org/W2316242722', 'https://openalex.org/W2327060713', 'https://openalex.org/W2336908123', 'https://openalex.org/W2337209831', 'https://openalex.org/W2341031032', 'https://openalex.org/W2342569126', 'https://openalex.org/W2342688693', 'https://openalex.org/W2346039638', 'https://openalex.org/W2403998898', 'https://openalex.org/W2414771725', 'https://openalex.org/W2420247920', 'https://openalex.org/W2460179076', 'https://openalex.org/W2460656813', 'https://openalex.org/W2461220095', 'https://openalex.org/W2479766819', 'https://openalex.org/W2487426829', 'https://openalex.org/W2508716485', 'https://openalex.org/W2512004978', 'https://openalex.org/W2523536421', 'https://openalex.org/W2530715453', 'https://openalex.org/W2531153177', 'https://openalex.org/W2536896139', 'https://openalex.org/W2546587412', 'https://openalex.org/W2551589138', 'https://openalex.org/W2583934823', 'https://openalex.org/W2586159641', 'https://openalex.org/W2586862787', 'https://openalex.org/W2593435710', 'https://openalex.org/W2593934358', 'https://openalex.org/W2594408608', 'https://openalex.org/W2598882867', 'https://openalex.org/W2613751670', 'https://openalex.org/W2621007144', 'https://openalex.org/W2622114026', 'https://openalex.org/W2734629565', 'https://openalex.org/W2740569386', 'https://openalex.org/W2743314643', 'https://openalex.org/W2747774814', 'https://openalex.org/W275444623', 'https://openalex.org/W2754914396', 'https://openalex.org/W2765435739', 'https://openalex.org/W2769070560', 'https://openalex.org/W2769367424', 'https://openalex.org/W2772921794', 'https://openalex.org/W2783674487', 'https://openalex.org/W2790726106', 'https://openalex.org/W2793012170', 'https://openalex.org/W2795441313', 'https://openalex.org/W2795460644', 'https://openalex.org/W2797771854', 'https://openalex.org/W2798033749', 'https://openalex.org/W2800392236', 'https://openalex.org/W2800895026', 'https://openalex.org/W2801583180', 'https://openalex.org/W2802800648', 'https://openalex.org/W2803222773', 'https://openalex.org/W2803495457', 'https://openalex.org/W2804761030', 'https://openalex.org/W2806841724', 'https://openalex.org/W2808835040', 'https://openalex.org/W2884024959', 'https://openalex.org/W2886963239', 'https://openalex.org/W2887070153', 'https://openalex.org/W2887249435', 'https://openalex.org/W2890545987', 'https://openalex.org/W2891323842', 'https://openalex.org/W2898215009', 'https://openalex.org/W2898267230', 'https://openalex.org/W2900295924', 'https://openalex.org/W2900885634', 'https://openalex.org/W2901135258', 'https://openalex.org/W2901506506', 'https://openalex.org/W2903401896', 'https://openalex.org/W2905211300', 'https://openalex.org/W2908043015', 'https://openalex.org/W2908788147', 'https://openalex.org/W2911211113', 'https://openalex.org/W2913447289', 'https://openalex.org/W2914942635', 'https://openalex.org/W2915388966', 'https://openalex.org/W2917613203', 'https://openalex.org/W2918755080', 'https://openalex.org/W2918972495', 'https://openalex.org/W2921134377', 'https://openalex.org/W2923157655', 'https://openalex.org/W2925446906', 'https://openalex.org/W2931418311', 'https://openalex.org/W2939548416', 'https://openalex.org/W2940985092', 'https://openalex.org/W2941124580', 'https://openalex.org/W2941855124', 'https://openalex.org/W2944755088', 'https://openalex.org/W2946428860', 'https://openalex.org/W2947732043', 'https://openalex.org/W2947989913', 'https://openalex.org/W2950856997', 'https://openalex.org/W2950996070', 'https://openalex.org/W2951546814', 'https://openalex.org/W2951890476', 'https://openalex.org/W2952214509', 'https://openalex.org/W2952708922', 'https://openalex.org/W2953008154', 'https://openalex.org/W2953258972', 'https://openalex.org/W2963789682', 'https://openalex.org/W2963825204', 'https://openalex.org/W2965386138', 'https://openalex.org/W2966172870', 'https://openalex.org/W2969494055', 'https://openalex.org/W2969664042', 'https://openalex.org/W2970087737', 'https://openalex.org/W2970250038', 'https://openalex.org/W2971161296', 'https://openalex.org/W2972600793', 'https://openalex.org/W2976994348', 'https://openalex.org/W2977499190', 'https://openalex.org/W2977816495', 'https://openalex.org/W2978209487', 'https://openalex.org/W2978670015', 'https://openalex.org/W2979620384', 'https://openalex.org/W2981382902', 'https://openalex.org/W2987834130', 'https://openalex.org/W2989637766', 'https://openalex.org/W3000733748', 'https://openalex.org/W3000877470', 'https://openalex.org/W3005494042', 'https://openalex.org/W3007977080', 'https://openalex.org/W3009846508', 'https://openalex.org/W3010972511', 'https://openalex.org/W3012307045', 'https://openalex.org/W3012887203', 'https://openalex.org/W3013924915', 'https://openalex.org/W3014483374', 'https://openalex.org/W3015767363', 'https://openalex.org/W3016485299', 'https://openalex.org/W3016825230', 'https://openalex.org/W3017351014', 'https://openalex.org/W3023438254', 'https://openalex.org/W3026033158', 'https://openalex.org/W3027826979', 'https://openalex.org/W3028644610', 'https://openalex.org/W3036473409', 'https://openalex.org/W3037719963', 'https://openalex.org/W3039936492', 'https://openalex.org/W3042448685', 'https://openalex.org/W3044049599', 'https://openalex.org/W3046879958', 'https://openalex.org/W3048074835', 'https://openalex.org/W3048596299', 'https://openalex.org/W3048746735', 'https://openalex.org/W3082136743', 'https://openalex.org/W3082529147', 'https://openalex.org/W3083525785', 'https://openalex.org/W3084269232', 'https://openalex.org/W3110809788', 'https://openalex.org/W3112365529', 'https://openalex.org/W3117516373', 'https://openalex.org/W3118432447', 'https://openalex.org/W3118685952', 'https://openalex.org/W3121085187', 'https://openalex.org/W3121252115', 'https://openalex.org/W3122882833', 'https://openalex.org/W3123647066', 'https://openalex.org/W3126399116', 'https://openalex.org/W3127556981', 'https://openalex.org/W3127626997', 'https://openalex.org/W3128200801', 'https://openalex.org/W3129247766', 'https://openalex.org/W3132478888', 'https://openalex.org/W3132592127', 'https://openalex.org/W3134334430', 'https://openalex.org/W3138010118', 'https://openalex.org/W3138215020', 'https://openalex.org/W3139518338', 'https://openalex.org/W3141884635', 'https://openalex.org/W3152004963', 'https://openalex.org/W3156550890', 'https://openalex.org/W3157791544', 'https://openalex.org/W3159434622', 'https://openalex.org/W3159598242', 'https://openalex.org/W3162293114', 'https://openalex.org/W3162773976', 'https://openalex.org/W3165139673', 'https://openalex.org/W3165287952', 'https://openalex.org/W3167580159', 'https://openalex.org/W3169544586', 'https://openalex.org/W3169699960', 'https://openalex.org/W3174470148', 'https://openalex.org/W3176314022', 'https://openalex.org/W3176690274', 'https://openalex.org/W3176889573', 'https://openalex.org/W3177957656', 'https://openalex.org/W3195024633', 'https://openalex.org/W3197271031', 'https://openalex.org/W3198816289', 'https://openalex.org/W3199759794', 'https://openalex.org/W3199793491', 'https://openalex.org/W3201488107', 'https://openalex.org/W3202187704', 'https://openalex.org/W3202436266', 'https://openalex.org/W3203332950', 'https://openalex.org/W3205209733', 'https://openalex.org/W3206344332', 'https://openalex.org/W3207447782', 'https://openalex.org/W3210819473', 'https://openalex.org/W3213012553', 'https://openalex.org/W3215022912', 'https://openalex.org/W3215745894', 'https://openalex.org/W3216700290', 'https://openalex.org/W402335930', 'https://openalex.org/W4205455694', 'https://openalex.org/W4210280122', 'https://openalex.org/W4210417953', 'https://openalex.org/W4213158923', 'https://openalex.org/W4220677986', 'https://openalex.org/W4220680634', 'https://openalex.org/W4220764901', 'https://openalex.org/W4224992124', 'https://openalex.org/W4225151349', 'https://openalex.org/W4225264529', 'https://openalex.org/W4225748550', 'https://openalex.org/W4225786597', 'https://openalex.org/W4229457572', 'https://openalex.org/W4235642752', 'https://openalex.org/W4282938578', 'https://openalex.org/W4282962148', 'https://openalex.org/W4283009135', 'https://openalex.org/W4283075240', 'https://openalex.org/W4283206827', 'https://openalex.org/W4283589795', 'https://openalex.org/W4285024399', 'https://openalex.org/W4285077403', 'https://openalex.org/W4285592339', 'https://openalex.org/W4285600552', 'https://openalex.org/W4286297399', 'https://openalex.org/W4293065133', 'https://openalex.org/W4293574555', 'https://openalex.org/W4295242484', 'https://openalex.org/W4297540219', 'https://openalex.org/W4301396398', 'https://openalex.org/W4306315509', 'https://openalex.org/W4306925897', 'https://openalex.org/W4309413267', 'https://openalex.org/W4309934757', 'https://openalex.org/W4313260635', 'https://openalex.org/W4313454095', 'https://openalex.org/W4313545327', 'https://openalex.org/W4368358570', 'https://openalex.org/W52073794', 'https://openalex.org/W634221467'], 'related_works': ['https://openalex.org/W4367320835', 'https://openalex.org/W4304688313', 'https://openalex.org/W4230745693', 'https://openalex.org/W4200511119', 'https://openalex.org/W2998655779', 'https://openalex.org/W2995533571', 'https://openalex.org/W2899084033', 'https://openalex.org/W2748952813', 'https://openalex.org/W2487966272', 'https://openalex.org/W2094739251'], 'abstract_inverted_index': {'In': [0], 'the': [1, 35, 44, 112, 127], 'last': [2], 'years,': [3], 'liquid': [4, 78], 'biopsy': [5, 52, 79], 'gained': [6], 'increasing': [7], 'clinical': [8, 124], 'relevance': [9], 'for': [10, 47, 61], 'detecting': [11], 'and': [12, 22, 32, 64, 72, 86, 94, 121, 150], 'monitoring': [13], 'several': [14], 'cancer': [15, 48], 'types,': [16], 'being': [17], 'minimally': [18], 'invasive,': [19, 54], 'highly': [20], 'informative': [21, 81], 'replicable': [23], 'over': [24], 'time.': [25], 'This': [26, 105], 'revolutionary': [27], 'approach': [28], 'can': [29, 65, 91], 'be': [30, 92], 'complementary': [31], 'may,': [33], 'in': [34, 100], 'future,': [36], 'replace': [37], 'tissue': [38, 51], 'biopsy,': [39], 'which': [40], 'is': [41, 53, 80], 'still': [42], 'considered': [43], 'gold': [45], 'standard': [46], 'diagnosis.': [49], '"Classical"': [50], 'often': [55], 'cannot': [56], 'provide': [57, 66, 108], 'sufficient': [58], 'bioptic': [59], 'material': [60], 'advanced': [62], 'screening,': [63], 'isolated': [67], 'information': [68], 'about': [69], 'disease': [70, 148], 'evolution': [71], 'heterogeneity.': [73], 'Recent': [74], 'literature': [75], 'highlighted': [76], 'how': [77], 'of': [82, 111, 129], 'proteomic,': [83], 'genomic,': [84], 'epigenetic,': [85], 'metabolic': [87], 'alterations.': [88], 'These': [89], 'biomarkers': [90, 120], 'detected': [93], 'investigated': [95], 'using': [96], 'single-omic': [97], 'and,': [98], 'recently,': [99], 'combination': [101], 'through': [102], 'multi-omic': [103], 'approaches.': [104], 'review': [106], 'will': [107, 138], 'an': [109, 130], 'overview': [110], 'most': [113], 'suitable': [114], 'techniques': [115], 'to': [116, 142], 'thoroughly': [117], 'characterize': [118], 'tumor': [119], 'their': [122], 'potential': [123], 'applications,': [125], 'highlighting': [126], 'importance': [128], 'integrated': [131], 'multi-omic,': [132], 'multi-analyte': [133], 'approach.': [134], 'Personalized': [135], 'medical': [136], 'investigations': [137], 'soon': [139], 'allow': [140], 'patients': [141], 'receive': [143], 'predictable': [144], 'prognostic': [145], 'evaluations,': [146], 'early': [147], 'diagnosis,': [149], 'subsequent': [151]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4362581199', 'counts_by_year': [{'year': 2024, 'cited_by_count': 13}, {'year': 2023, 'cited_by_count': 7}], 'updated_date': '2025-01-04T07:10:51.291303', 'created_date': '2023-04-06'}