Supplementary Figure S23 from Evolution of Castration-Resistant Prostate Cancer in ctDNA during Sequential Androgen Receptor Pathway Inhibition

Name: Work Video:
Duration: 3 min 30 s
Description: &lt;p&gt;Supplementary Figure S23 provides AR region copy number profiles for all 20 patients that showed a change in the structure of androgen receptor (AR) amplifications after treatment with abiraterone/enzalutamide&lt;/p&gt;
Matti Annala; Sinja Taavitsainen; Daniel Khalaf; Gillian Vandekerkhove; Kevin Beja; Joonatan Sipola; Evan W. Warner; Cameron Herberts; Amanda Wong; Simon Fu; Daygen L. Finch; Conrad D. Oja; Joanna Vergidis; Muhammad Zulfiqar; Bernhard J. Eigl; Christian K. Kollmansberger; Matti Nykter; Martin Gleave; Kim N.; Alexander W. Wyatt
{'id': 'https://openalex.org/W4361940014', 'doi': 'https://doi.org/10.1158/1078-0432.22481801.v1', 'title': 'Supplementary Figure S23 from Evolution of Castration-Resistant Prostate Cancer in ctDNA during Sequential Androgen Receptor Pathway Inhibition', 'display_name': 'Supplementary Figure S23 from Evolution of Castration-Resistant Prostate Cancer in ctDNA during Sequential Androgen Receptor Pathway Inhibition', 'publication_year': 2023, 'publication_date': '2023-03-31', 'ids': {'openalex': 'https://openalex.org/W4361940014', 'doi': 'https://doi.org/10.1158/1078-0432.22481801.v1'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.22481801.v1', 'pdf_url': 'https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S23_from_Evolution_of_Castration-Resistant_Prostate_Cancer_in_ctDNA_during_Sequential_Androgen_Receptor_Pathway_Inhibition/22481801/1/files/39933314.pdf', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'type': 'preprint', 'type_crossref': 'posted-content', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S23_from_Evolution_of_Castration-Resistant_Prostate_Cancer_in_ctDNA_during_Sequential_Androgen_Receptor_Pathway_Inhibition/22481801/1/files/39933314.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5044585372', 'display_name': 'Matti Annala', 'orcid': 'https://orcid.org/0000-0001-8478-9026'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Matti Annala', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034199909', 'display_name': 'Sinja Taavitsainen', 'orcid': 'https://orcid.org/0000-0001-7559-9853'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Sinja Taavitsainen', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042163217', 'display_name': 'Daniel Khalaf', 'orcid': 'https://orcid.org/0000-0001-6329-2678'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Daniel J. Khalaf', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059943416', 'display_name': 'Gillian Vandekerkhove', 'orcid': 'https://orcid.org/0000-0001-5606-0908'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Gillian Vandekerkhove', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007090230', 'display_name': 'Kevin Beja', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kevin Beja', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027045057', 'display_name': 'Joonatan Sipola', 'orcid': 'https://orcid.org/0000-0003-1438-9988'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Joonatan Sipola', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091420133', 'display_name': 'Evan W. Warner', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Evan W. Warner', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085008756', 'display_name': 'Cameron Herberts', 'orcid': 'https://orcid.org/0000-0002-9929-8374'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Cameron Herberts', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002339848', 'display_name': 'Amanda Wong', 'orcid': 'https://orcid.org/0000-0003-3190-7847'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Amanda Wong', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082601600', 'display_name': 'Simon Fu', 'orcid': 'https://orcid.org/0000-0001-7017-0572'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Simon Fu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006541874', 'display_name': 'Daygen L. Finch', 'orcid': 'https://orcid.org/0000-0002-9442-7608'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Daygen L. Finch', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061538086', 'display_name': 'Conrad D. Oja', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Conrad D. Oja', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020465724', 'display_name': 'Joanna Vergidis', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Joanna Vergidis', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102508039', 'display_name': 'Muhammad Zulfiqar', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Muhammad Zulfiqar', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089306688', 'display_name': 'Bernhard J. Eigl', 'orcid': 'https://orcid.org/0000-0003-1653-6929'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Bernhard J. Eigl', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018856250', 'display_name': 'Christian K. Kollmansberger', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Christian K. Kollmansberger', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063194021', 'display_name': 'Matti Nykter', 'orcid': 'https://orcid.org/0000-0001-6956-2843'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Matti Nykter', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062125605', 'display_name': 'Martin Gleave', 'orcid': 'https://orcid.org/0000-0003-4235-0167'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Martin E. Gleave', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005231494', 'display_name': 'Kim N.', 'orcid': 'https://orcid.org/0000-0002-3782-7226'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kim N. Chi', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5055207707', 'display_name': 'Alexander W. Wyatt', 'orcid': 'https://orcid.org/0000-0003-2399-0329'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Alexander W. Wyatt', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 68}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11287', 'display_name': 'Cancer Genomics and Diagnostics', 'score': 0.934, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/enzalutamide', 'display_name': 'Enzalutamide', 'score': 0.9851068}, {'id': 'https://openalex.org/keywords/abiraterone', 'display_name': 'Abiraterone', 'score': 0.661039}], 'concepts': [{'id': 'https://openalex.org/C2776551883', 'wikidata': 'https://www.wikidata.org/wiki/Q1996756', 'display_name': 'Enzalutamide', 'level': 5, 'score': 0.9851068}, {'id': 'https://openalex.org/C61367390', 'wikidata': 'https://www.wikidata.org/wiki/Q416601', 'display_name': 'Androgen receptor', 'level': 4, 'score': 0.90066326}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.79699016}, {'id': 'https://openalex.org/C2776421732', 'wikidata': 'https://www.wikidata.org/wiki/Q27888393', 'display_name': 'Abiraterone', 'level': 5, 'score': 0.661039}, {'id': 'https://openalex.org/C2777911890', 'wikidata': 'https://www.wikidata.org/wiki/Q62614', 'display_name': 'Androgen', 'level': 3, 'score': 0.5212489}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.4846335}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4401212}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.37871712}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.36783713}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36381286}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.36222577}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3469336}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.2338514}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.10296333}], 'mesh': [], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.22481801.v1', 'pdf_url': 'https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S23_from_Evolution_of_Castration-Resistant_Prostate_Cancer_in_ctDNA_during_Sequential_Androgen_Receptor_Pathway_Inhibition/22481801/1/files/39933314.pdf', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.ccr-21-1625', 'pdf_url': 'https://aacrjournals.org/clincancerres/article-pdf/27/16/4610/3083980/4610.pdf', 'source': None, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://figshare.com/articles/journal_contribution/Supplementary_Figure_S23_from_Evolution_of_Castration-Resistant_Prostate_Cancer_in_ctDNA_during_Sequential_Androgen_Receptor_Pathway_Inhibition/22481801', 'pdf_url': 'https://figshare.com/articles/journal_contribution/Supplementary_Figure_S23_from_Evolution_of_Castration-Resistant_Prostate_Cancer_in_ctDNA_during_Sequential_Androgen_Receptor_Pathway_Inhibition/22481801/1/files/39933314.pdf', 'source': {'id': 'https://openalex.org/S4306400572', 'display_name': 'OPAL (Open@LaTrobe) (La Trobe University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I196829312', 'host_organization_name': 'La Trobe University', 'host_organization_lineage': ['https://openalex.org/I196829312'], 'host_organization_lineage_names': ['La Trobe University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.22481801.v1', 'pdf_url': 'https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S23_from_Evolution_of_Castration-Resistant_Prostate_Cancer_in_ctDNA_during_Sequential_Androgen_Receptor_Pathway_Inhibition/22481801/1/files/39933314.pdf', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'score': 0.68, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4361890616', 'https://openalex.org/W3201841018', 'https://openalex.org/W3122236002', 'https://openalex.org/W3042787857', 'https://openalex.org/W3037653349', 'https://openalex.org/W2917061290', 'https://openalex.org/W2584454163', 'https://openalex.org/W2547028490', 'https://openalex.org/W2514821758', 'https://openalex.org/W2055548310'], 'abstract_inverted_index': {'&lt;p&gt;Supplementary': [0], 'Figure': [1], 'S23': [2], 'provides': [3], 'AR': [4], 'region': [5], 'copy': [6], 'number': [7], 'profiles': [8], 'for': [9], 'all': [10], '20': [11], 'patients': [12], 'that': [13], 'showed': [14], 'a': [15], 'change': [16], 'in': [17], 'the': [18], 'structure': [19], 'of': [20], 'androgen': [21], 'receptor': [22], '(AR)': [23], 'amplifications': [24], 'after': [25], 'treatment': [26], 'with': [27], 'abiraterone/enzalutamide&lt;/p&gt;': [28]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4361940014', 'counts_by_year': [], 'updated_date': '2024-12-14T19:34:08.470033', 'created_date': '2023-04-05'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
