Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2917061290', 'doi': 'https://doi.org/10.1016/j.euf.2019.02.011', 'title': 'Germline DNA-repair Gene Mutations and Efficacy of Abiraterone or Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer', 'display_name': 'Germline DNA-repair Gene Mutations and Efficacy of Abiraterone or Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer', 'publication_year': 2019, 'publication_date': '2019-02-23', 'ids': {'openalex': 'https://openalex.org/W2917061290', 'doi': 'https://doi.org/10.1016/j.euf.2019.02.011', 'mag': '2917061290', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30797739'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.euf.2019.02.011', 'pdf_url': 'http://www.eu-focus.europeanurology.com/article/S2405456919300318/pdf', 'source': {'id': 'https://openalex.org/S2764909046', 'display_name': 'European Urology Focus', 'issn_l': '2405-4569', 'issn': ['2405-4569'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.eu-focus.europeanurology.com/article/S2405456919300318/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101498963', 'display_name': 'Ning Shao', 'orcid': 'https://orcid.org/0000-0003-2534-1277'}, 'institutions': [{'id': 'https://openalex.org/I4210093194', 'display_name': 'Fudan University Shanghai Cancer Center', 'ror': 'https://ror.org/00my25942', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093194']}, {'id': 'https://openalex.org/I133868755', 'display_name': 'Shanghai Medical College of Fudan University', 'ror': 'https://ror.org/01zntxs11', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I133868755', 'https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ning Shao', 'raw_affiliation_strings': ['Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China', 'Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210093194']}, {'raw_affiliation_string': 'Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China', 'institution_ids': ['https://openalex.org/I133868755']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016243869', 'display_name': 'Yao Zhu', 'orcid': 'https://orcid.org/0000-0001-7950-6669'}, 'institutions': [{'id': 'https://openalex.org/I133868755', 'display_name': 'Shanghai Medical College of Fudan University', 'ror': 'https://ror.org/01zntxs11', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I133868755', 'https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I4210093194', 'display_name': 'Fudan University Shanghai Cancer Center', 'ror': 'https://ror.org/00my25942', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093194']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Yao Zhu', 'raw_affiliation_strings': ['Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China', 'Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China', 'institution_ids': ['https://openalex.org/I133868755']}, {'raw_affiliation_string': 'Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210093194']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113761687', 'display_name': 'Ding Wei Ye', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I133868755', 'display_name': 'Shanghai Medical College of Fudan University', 'ror': 'https://ror.org/01zntxs11', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I133868755', 'https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I4210093194', 'display_name': 'Fudan University Shanghai Cancer Center', 'ror': 'https://ror.org/00my25942', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093194']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Ding Wei Ye', 'raw_affiliation_strings': ['Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China', 'Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China', 'institution_ids': ['https://openalex.org/I133868755']}, {'raw_affiliation_string': 'Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210093194']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5016243869', 'https://openalex.org/A5113761687'], 'corresponding_institution_ids': ['https://openalex.org/I133868755', 'https://openalex.org/I4210093194', 'https://openalex.org/I133868755', 'https://openalex.org/I4210093194'], 'apc_list': {'value': 3800, 'currency': 'USD', 'value_usd': 3800, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.049, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.120779, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 61, 'max': 69}, 'biblio': {'volume': '5', 'issue': '5', 'first_page': '745', 'last_page': '747'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11914', 'display_name': 'PARP inhibition in cancer therapy', 'score': 0.9912, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11146', 'display_name': 'Hormonal and reproductive studies', 'score': 0.9586, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/enzalutamide', 'display_name': 'Enzalutamide', 'score': 0.9927727}, {'id': 'https://openalex.org/keywords/abiraterone', 'display_name': 'Abiraterone', 'score': 0.9299664}], 'concepts': [{'id': 'https://openalex.org/C2776551883', 'wikidata': 'https://www.wikidata.org/wiki/Q1996756', 'display_name': 'Enzalutamide', 'level': 5, 'score': 0.9927727}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9377201}, {'id': 'https://openalex.org/C2776421732', 'wikidata': 'https://www.wikidata.org/wiki/Q27888393', 'display_name': 'Abiraterone', 'level': 5, 'score': 0.9299664}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.854543}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.5911789}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.51449466}, {'id': 'https://openalex.org/C109825262', 'wikidata': 'https://www.wikidata.org/wiki/Q1139164', 'display_name': 'Germline', 'level': 3, 'score': 0.45842186}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.3799354}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.3781314}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.34854507}, {'id': 'https://openalex.org/C61367390', 'wikidata': 'https://www.wikidata.org/wiki/Q416601', 'display_name': 'Androgen receptor', 'level': 4, 'score': 0.20640123}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.060410142}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000736', 'descriptor_name': 'Androstenes', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D010669', 'descriptor_name': 'Phenylthiohydantoin', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000736', 'descriptor_name': 'Androstenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005854', 'descriptor_name': 'Germ Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009362', 'descriptor_name': 'Neoplasm Metastasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010669', 'descriptor_name': 'Phenylthiohydantoin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010669', 'descriptor_name': 'Phenylthiohydantoin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D064129', 'descriptor_name': 'Prostatic Neoplasms, Castration-Resistant', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.euf.2019.02.011', 'pdf_url': 'http://www.eu-focus.europeanurology.com/article/S2405456919300318/pdf', 'source': {'id': 'https://openalex.org/S2764909046', 'display_name': 'European Urology Focus', 'issn_l': '2405-4569', 'issn': ['2405-4569'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30797739', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.euf.2019.02.011', 'pdf_url': 'http://www.eu-focus.europeanurology.com/article/S2405456919300318/pdf', 'source': {'id': 'https://openalex.org/S2764909046', 'display_name': 'European Urology Focus', 'issn_l': '2405-4569', 'issn': ['2405-4569'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.83}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81370073'}], 'datasets': [], 'versions': [], 'referenced_works_count': 4, 'referenced_works': ['https://openalex.org/W2593176248', 'https://openalex.org/W2779062531', 'https://openalex.org/W2786529129', 'https://openalex.org/W2787607836'], 'related_works': ['https://openalex.org/W4281801213', 'https://openalex.org/W4249309765', 'https://openalex.org/W3201841018', 'https://openalex.org/W3122236002', 'https://openalex.org/W3042787857', 'https://openalex.org/W2917061290', 'https://openalex.org/W2584454163', 'https://openalex.org/W2547028490', 'https://openalex.org/W2514821758', 'https://openalex.org/W2479406918'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2917061290', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}], 'updated_date': '2024-12-19T19:26:12.944762', 'created_date': '2019-03-02'}