Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4324129016', 'doi': 'https://doi.org/10.1128/aac.01601-22', 'title': 'Molecular Markers of Sulfadoxine-Pyrimethamine Resistance in Samples from Children with Uncomplicated Plasmodium falciparum at Three Sites in Angola in 2019', 'display_name': 'Molecular Markers of Sulfadoxine-Pyrimethamine Resistance in Samples from Children with Uncomplicated Plasmodium falciparum at Three Sites in Angola in 2019', 'publication_year': 2023, 'publication_date': '2023-04-18', 'ids': {'openalex': 'https://openalex.org/W4324129016', 'doi': 'https://doi.org/10.1128/aac.01601-22', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36916920'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01601-22', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://doi.org/10.1128/aac.01601-22', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027449462', 'display_name': 'Stefano R. Rosillo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1289490764', 'display_name': 'Centers for Disease Control and Prevention', 'ror': 'https://ror.org/042twtr12', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stefano R. Rosillo', 'raw_affiliation_strings': ['Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA'], 'affiliations': [{'raw_affiliation_string': 'Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'institution_ids': ['https://openalex.org/I1289490764']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101661843', 'display_name': 'Filomeno Fortes', 'orcid': 'https://orcid.org/0000-0002-1483-7835'}, 'institutions': [{'id': 'https://openalex.org/I4210160660', 'display_name': 'Ministry of Health', 'ror': 'https://ror.org/04es3ne34', 'country_code': 'AO', 'type': 'government', 'lineage': ['https://openalex.org/I4210160660']}], 'countries': ['AO'], 'is_corresponding': False, 'raw_author_name': 'Pedro Rafael Dimbu', 'raw_affiliation_strings': ['National Malaria Control Program, Ministry of Health, Luanda, Angola'], 'affiliations': [{'raw_affiliation_string': 'National Malaria Control Program, Ministry of Health, Luanda, Angola', 'institution_ids': ['https://openalex.org/I4210160660']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021960547', 'display_name': 'Ana Luísa Micolo Cândido', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210160660', 'display_name': 'Ministry of Health', 'ror': 'https://ror.org/04es3ne34', 'country_code': 'AO', 'type': 'government', 'lineage': ['https://openalex.org/I4210160660']}], 'countries': ['AO'], 'is_corresponding': False, 'raw_author_name': 'Ana Luisa M. Cândido', 'raw_affiliation_strings': ['National Institute of Health Research, Ministry of Health, Luanda, Angola'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Health Research, Ministry of Health, Luanda, Angola', 'institution_ids': ['https://openalex.org/I4210160660']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083534622', 'display_name': 'Je-Hoon Michael Oh', 'orcid': 'https://orcid.org/0009-0009-6824-7396'}, 'institutions': [{'id': 'https://openalex.org/I1289490764', 'display_name': 'Centers for Disease Control and Prevention', 'ror': 'https://ror.org/042twtr12', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Je-Hoon Michael Oh', 'raw_affiliation_strings': ['Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA'], 'affiliations': [{'raw_affiliation_string': 'Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'institution_ids': ['https://openalex.org/I1289490764']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035702769', 'display_name': 'Carolina Miguel Ferreira', 'orcid': None}, 'institutions': [], 'countries': ['AO'], 'is_corresponding': False, 'raw_author_name': 'Carolina Miguel Ferreira', 'raw_affiliation_strings': ['Population Services International Angola, Luanda, Angola'], 'affiliations': [{'raw_affiliation_string': 'Population Services International Angola, Luanda, Angola', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091802513', 'display_name': 'Benjamin Nieto Andrade', 'orcid': None}, 'institutions': [], 'countries': ['AO'], 'is_corresponding': False, 'raw_author_name': 'Benjamin Nieto Andrade', 'raw_affiliation_strings': ['Population Services International Angola, Luanda, Angola'], 'affiliations': [{'raw_affiliation_string': 'Population Services International Angola, Luanda, Angola', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087086166', 'display_name': 'Sarah M. Labuda', 'orcid': 'https://orcid.org/0000-0002-3312-681X'}, 'institutions': [{'id': 'https://openalex.org/I4210107484', 'display_name': "U.S. President's Malaria Initiative", 'ror': 'https://ror.org/012rb2c33', 'country_code': 'US', 'type': 'other', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934', 'https://openalex.org/I2801582665', 'https://openalex.org/I4210107484']}, {'id': 'https://openalex.org/I1289490764', 'display_name': 'Centers for Disease Control and Prevention', 'ror': 'https://ror.org/042twtr12', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sarah Labuda', 'raw_affiliation_strings': ['United States President’s Malaria Initiative, U.S. Centers for Disease Control and Prevention, Luanda, Angola'], 'affiliations': [{'raw_affiliation_string': 'United States President’s Malaria Initiative, U.S. Centers for Disease Control and Prevention, Luanda, Angola', 'institution_ids': ['https://openalex.org/I4210107484', 'https://openalex.org/I1289490764']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088657666', 'display_name': 'Roberta Horth', 'orcid': 'https://orcid.org/0000-0003-1810-2542'}, 'institutions': [{'id': 'https://openalex.org/I1289490764', 'display_name': 'Centers for Disease Control and Prevention', 'ror': 'https://ror.org/042twtr12', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Roberta Horth', 'raw_affiliation_strings': ['Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA'], 'affiliations': [{'raw_affiliation_string': 'Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'institution_ids': ['https://openalex.org/I1289490764']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051935923', 'display_name': 'Julia Kelley', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1289490764', 'display_name': 'Centers for Disease Control and Prevention', 'ror': 'https://ror.org/042twtr12', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Julia Kelley', 'raw_affiliation_strings': ['Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA'], 'affiliations': [{'raw_affiliation_string': 'Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'institution_ids': ['https://openalex.org/I1289490764']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058185193', 'display_name': 'Joana Morais', 'orcid': 'https://orcid.org/0000-0002-4524-4055'}, 'institutions': [{'id': 'https://openalex.org/I4210160660', 'display_name': 'Ministry of Health', 'ror': 'https://ror.org/04es3ne34', 'country_code': 'AO', 'type': 'government', 'lineage': ['https://openalex.org/I4210160660']}], 'countries': ['AO'], 'is_corresponding': False, 'raw_author_name': 'Joana F. M. Morais', 'raw_affiliation_strings': ['National Institute of Health Research, Ministry of Health, Luanda, Angola'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Health Research, Ministry of Health, Luanda, Angola', 'institution_ids': ['https://openalex.org/I4210160660']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101661843', 'display_name': 'Filomeno Fortes', 'orcid': 'https://orcid.org/0000-0002-1483-7835'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Filomeno Fortes', 'raw_affiliation_strings': ['Institute of Hygiene and Tropical Medicine, Nova University of Lisbon, Lisbon, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Institute of Hygiene and Tropical Medicine, Nova University of Lisbon, Lisbon, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051733815', 'display_name': 'José Franco Martins', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210160660', 'display_name': 'Ministry of Health', 'ror': 'https://ror.org/04es3ne34', 'country_code': 'AO', 'type': 'government', 'lineage': ['https://openalex.org/I4210160660']}], 'countries': ['AO'], 'is_corresponding': False, 'raw_author_name': 'José Franco Martins', 'raw_affiliation_strings': ['National Malaria Control Program, Ministry of Health, Luanda, Angola'], 'affiliations': [{'raw_affiliation_string': 'National Malaria Control Program, Ministry of Health, Luanda, Angola', 'institution_ids': ['https://openalex.org/I4210160660']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060841929', 'display_name': 'Eldin Talundzic', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1289490764', 'display_name': 'Centers for Disease Control and Prevention', 'ror': 'https://ror.org/042twtr12', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eldin Talundzic', 'raw_affiliation_strings': ['Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA'], 'affiliations': [{'raw_affiliation_string': 'Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'institution_ids': ['https://openalex.org/I1289490764']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063061996', 'display_name': 'Mateusz M. Pluciński', 'orcid': 'https://orcid.org/0000-0002-7322-4625'}, 'institutions': [{'id': 'https://openalex.org/I1289490764', 'display_name': 'Centers for Disease Control and Prevention', 'ror': 'https://ror.org/042twtr12', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934']}, {'id': 'https://openalex.org/I4210107484', 'display_name': "U.S. President's Malaria Initiative", 'ror': 'https://ror.org/012rb2c33', 'country_code': 'US', 'type': 'other', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934', 'https://openalex.org/I2801582665', 'https://openalex.org/I4210107484']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Mateusz M. Pluciński', 'raw_affiliation_strings': ['Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'United States President’s Malaria Initiative, Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA'], 'affiliations': [{'raw_affiliation_string': 'United States President’s Malaria Initiative, Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'institution_ids': ['https://openalex.org/I1289490764', 'https://openalex.org/I4210107484']}, {'raw_affiliation_string': 'Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA', 'institution_ids': ['https://openalex.org/I1289490764']}]}], 'countries_distinct_count': 3, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5063061996'], 'corresponding_institution_ids': ['https://openalex.org/I1289490764', 'https://openalex.org/I4210107484'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.988, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.75468, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 71, 'max': 82}, 'biblio': {'volume': '67', 'issue': '4', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10166', 'display_name': 'Global Impact of Arboviral Diseases', 'score': 0.9739, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10695', 'display_name': 'Global Impact of Helminth Infections and Control Strategies', 'score': 0.9509, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dihydropteroate-synthase', 'display_name': 'Dihydropteroate synthase', 'score': 0.96679455}, {'id': 'https://openalex.org/keywords/sulfadoxine/pyrimethamine', 'display_name': 'Sulfadoxine/pyrimethamine', 'score': 0.9432477}, {'id': 'https://openalex.org/keywords/sulfadoxine', 'display_name': 'Sulfadoxine', 'score': 0.7902138}, {'id': 'https://openalex.org/keywords/dihydrofolate-reductase', 'display_name': 'Dihydrofolate reductase', 'score': 0.66728425}, {'id': 'https://openalex.org/keywords/dhps', 'display_name': 'DHPS', 'score': 0.5185002}, {'id': 'https://openalex.org/keywords/artemisinin-resistance', 'display_name': 'Artemisinin Resistance', 'score': 0.461003}], 'concepts': [{'id': 'https://openalex.org/C2777234095', 'wikidata': 'https://www.wikidata.org/wiki/Q5276443', 'display_name': 'Dihydropteroate synthase', 'level': 5, 'score': 0.96679455}, {'id': 'https://openalex.org/C2780441369', 'wikidata': 'https://www.wikidata.org/wiki/Q421072', 'display_name': 'Sulfadoxine/pyrimethamine', 'level': 5, 'score': 0.9432477}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.85531783}, {'id': 'https://openalex.org/C2778301690', 'wikidata': 'https://www.wikidata.org/wiki/Q411557', 'display_name': 'Sulfadoxine', 'level': 5, 'score': 0.7902138}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.7460407}, {'id': 'https://openalex.org/C2781320022', 'wikidata': 'https://www.wikidata.org/wiki/Q417149', 'display_name': 'Dihydrofolate reductase', 'level': 3, 'score': 0.66728425}, {'id': 'https://openalex.org/C2776120307', 'wikidata': 'https://www.wikidata.org/wiki/Q426921', 'display_name': 'Artemisinin', 'level': 4, 'score': 0.6438652}, {'id': 'https://openalex.org/C2777035104', 'wikidata': 'https://www.wikidata.org/wiki/Q421072', 'display_name': 'Pyrimethamine', 'level': 4, 'score': 0.628537}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5693649}, {'id': 'https://openalex.org/C2780866276', 'wikidata': 'https://www.wikidata.org/wiki/Q7761386', 'display_name': 'DHPS', 'level': 4, 'score': 0.5185002}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.50707006}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.49588785}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.2879725}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.19467324}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.17617536}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.14707312}], 'mesh': [{'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000810', 'descriptor_name': 'Angola', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004338', 'descriptor_name': 'Drug Combinations', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011739', 'descriptor_name': 'Pyrimethamine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011739', 'descriptor_name': 'Pyrimethamine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D011739', 'descriptor_name': 'Pyrimethamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013413', 'descriptor_name': 'Sulfadoxine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013413', 'descriptor_name': 'Sulfadoxine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D013413', 'descriptor_name': 'Sulfadoxine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013762', 'descriptor_name': 'Tetrahydrofolate Dehydrogenase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013762', 'descriptor_name': 'Tetrahydrofolate Dehydrogenase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01601-22', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10362/155095', 'pdf_url': 'https://run.unl.pt/bitstream/10362/155095/1/Molecular_Markers_of_Sulfadoxine_Pyrimethamine_Resistance_in_Samples_from_Children_with_Uncomplicated_Plasmodium_falciparum_at_Three_Sites_in_Angola_in_2019.pdf', 'source': {'id': 'https://openalex.org/S4306400678', 'display_name': "Universidade Nova de Lisboa's Repository (Universidade Nova de Lisboa)", 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I83558840', 'host_organization_name': 'Universidade Nova de Lisboa', 'host_organization_lineage': ['https://openalex.org/I83558840'], 'host_organization_lineage_names': ['Universidade Nova de Lisboa'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112138', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36916920', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01601-22', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.86}], 'grants': [{'funder': 'https://openalex.org/F4320334467', 'funder_display_name': "President's Malaria Initiative", 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 22, 'referenced_works': ['https://openalex.org/W1808142626', 'https://openalex.org/W1996551849', 'https://openalex.org/W2021007121', 'https://openalex.org/W2047009134', 'https://openalex.org/W2080499055', 'https://openalex.org/W2101014912', 'https://openalex.org/W2106552226', 'https://openalex.org/W2107150651', 'https://openalex.org/W2137764200', 'https://openalex.org/W2144382724', 'https://openalex.org/W2257185490', 'https://openalex.org/W2527516004', 'https://openalex.org/W2611445687', 'https://openalex.org/W2741139908', 'https://openalex.org/W2788649440', 'https://openalex.org/W2793378655', 'https://openalex.org/W3021000798', 'https://openalex.org/W3097818497', 'https://openalex.org/W3145352161', 'https://openalex.org/W4206580515', 'https://openalex.org/W4307909808', 'https://openalex.org/W4312213759'], 'related_works': ['https://openalex.org/W343359807', 'https://openalex.org/W2169971066', 'https://openalex.org/W2163496117', 'https://openalex.org/W2161023750', 'https://openalex.org/W2160884305', 'https://openalex.org/W2142611140', 'https://openalex.org/W2122025531', 'https://openalex.org/W2099198335', 'https://openalex.org/W2076702075', 'https://openalex.org/W2071882002'], 'abstract_inverted_index': {'Sulfadoxine-pyrimethamine': [0], '(SP)': [1], 'is': [2], 'used': [3], 'for': [4], 'prevention': [5], 'of': [6, 41], 'malaria': [7], 'in': [8, 11, 31, 34, 46], 'pregnant': [9], 'women': [10], 'Angola.': [12], 'We': [13], 'sequenced': [14], 'the': [15], 'Plasmodium': [16], 'falciparum': [17], 'dihydrofolate': [18], 'reductase': [19], '(': [20, 26], 'pfdhfr': [21], ')': [22, 28], 'and': [23, 50], 'dihydropteroate': [24], 'synthase': [25], 'pfdhps': [27], 'genes,': [29], 'implicated': [30], 'SP': [32], 'resistance,': [33], 'samples': [35], 'collected': [36], 'during': [37], 'a': [38], '2019': [39], 'study': [40], 'artemisinin-based': [42], 'combination': [43], 'therapy': [44], 'efficacy': [45], 'Benguela,': [47], 'Lunda': [48], 'Sul,': [49], 'Zaire': [51], 'provinces.': [52]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4324129016', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-09-12T10:52:37.724523', 'created_date': '2023-03-15'}