Dihydrofolate reductase - AILBRY

Results for 'Dihydrofolate reductase' :

The Dynamic Energy Landscape of Dihydrofolate Reductase Catalysis

Publication Year: 2006

DOI: https://doi.org/10.1126/science.1130258

Abstract:

Authors:
- David D. Boehr
- Dan McElheny
- H. Jane Dyson
- Peter E. Wright
Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase‐trimethoprim, a drug‐receptor system

Publication Year: 1988

DOI: https://doi.org/10.1002/prot.340040106

Abstract:

Authors:
- Pnina Dauber‐Osguthorpe
- Victoria A. Roberts
- David J. Osguthorpe
- Jon A. Wolff
- M. Genest
- A. T. Hagler
Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

Publication Year: 1980

DOI: https://doi.org/10.1073/pnas.77.7.4216

Abstract:

Authors:
- G Urlaub
- Lawrence A. Chasin
Structure, Dynamics, and Catalytic Function of Dihydrofolate Reductase

Publication Year: 2004

DOI: https://doi.org/10.1146/annurev.biophys.33.110502.133613

Abstract:

Authors:
- Jason R. Schnell
- H. Jane Dyson
- Peter E. Wright
Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript

Publication Year: 2007

DOI: https://doi.org/10.1038/nature05519

Abstract:

Authors:
- Igor Martianov
- Aroul Ramadass
- Ana Serra Barros
- Natalie Chow
- Alexandre Akoulitchev
Dihydrofolate reductase as a therapeutic target

Publication Year: 1990

DOI: https://doi.org/10.1096/fasebj.4.8.2185970

Abstract:

Authors:
- Barry Schweitzer
- Adam P. Dicker
- Joseph R. Bertino
Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

Publication Year: 1983

DOI: https://doi.org/10.1073/pnas.80.9.2495

Abstract:

Authors:
- Christian C. Simonsen
- Arthur D. Levinson
Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

Publication Year: 1978

DOI: https://doi.org/10.1016/s0021-9258(17)34875-5

Abstract:

Authors:
- F W Alt
- Rodney E. Kellems
- Joseph R. Bertino
- Robert Schimke
Pyrimethamine and Proguanil Resistance-Conferring Mutations in Plasmodium falciparum Dihydrofolate Reductase: Polymerase Chain Reaction Methods for Surveillance in Africa

Publication Year: 1995

DOI: https://doi.org/10.4269/ajtmh.1995.52.565

Abstract:

Authors:
- Christopher V. Plowe
- Abdoulaye Djimdé
- Madama Bouaré
- Ogobara K. Doumbo
- Thomas E. Wellems
Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

Publication Year: 1982

DOI: https://doi.org/10.1016/s0021-9258(18)33497-5

Abstract:

Authors:
- J.T. Bolin
- David J. Filman
- David A. Matthews
- R. Hamlin
- J. Kraut
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.

Publication Year: 1988

DOI: https://doi.org/10.1073/pnas.85.23.9114

Abstract:

Authors:
- David S. Peterson
- David Walliker
- Thomas E. Wellems
Loop and Subdomain Movements in the Mechanism of Escherichia coli Dihydrofolate Reductase: Crystallographic Evidence,

Publication Year: 1997

DOI: https://doi.org/10.1021/bi962337c

Abstract:

Authors:
- M.R. Sawaya
- Joseph Kraut
Dihydrofolate reductase inhibitors as antibacterial agents

Publication Year: 2005

DOI: https://doi.org/10.1016/j.bcp.2005.10.052

Abstract:

Authors:
- Stephen Hawser
- Sergio Lociuro
- Khalid Islam
Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

Publication Year: 1987

DOI: https://doi.org/10.1021/bi00387a052

Abstract:

Authors:
- Carol A. Fierke
- Kenneth A. Johnson
- Stephen J. Benkovic
Nucleotide sequence of the E. coli gene coding for dihydrofolate reductase

Publication Year: 1980

DOI: https://doi.org/10.1093/nar/8.10.2255

Abstract:

Authors:
- Douglas R. Smith
- Joseph M. Calvo

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Results for 'Dihydrofolate reductase' :

The Dynamic Energy Landscape of Dihydrofolate Reductase Catalysis

Structure and energetics of ligand binding to proteins: <i>Escherichia coli</i> dihydrofolate reductase‐trimethoprim, a drug‐receptor system

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

Structure, Dynamics, and Catalytic Function of Dihydrofolate Reductase

Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript

Dihydrofolate reductase as a therapeutic target

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

Pyrimethamine and Proguanil Resistance-Conferring Mutations in Plasmodium falciparum Dihydrofolate Reductase: Polymerase Chain Reaction Methods for Surveillance in Africa

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.

Loop and Subdomain Movements in the Mechanism of <i>Escherichia coli </i>Dihydrofolate Reductase: Crystallographic Evidence<sup>,</sup>

Dihydrofolate reductase inhibitors as antibacterial agents

Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

Nucleotide sequence of the E. coli gene coding for dihydrofolate reductase

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