Transcriptional Biomarkers of Differentially Detectable Mycobacterium tuberculosis in Patient Sputum

Name: Work Video:
Duration: 3 min 30 s
Description: Certain populations of Mycobacterium tuberculosis go undetected by standard diagnostics but can be enumerated using limiting dilution assays. These differentially detectable M. tuberculosis (DD M. tuberculosis) populations may have relevance for persistence due to their drug tolerance. It is unclear how well DD M. tuberculosis from patients is modeled by a recently developed
Kayvan Zainabadi; Kohta Saito; Saurabh Mishra; Kathleen F. Walsh; L Mathurin; Stalz Charles Vilbrun; Oksana Ocheretina; Jean W. Pape; Daniel W. Fitzgerald; Carl Nathan; Myung Hee Lee
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