Abstract:Troponins are muscle proteins that assist muscle contraction regulation. There are two troponins that exist primarily in cardiac muscle: cardiac troponin T (cTnT) and cardiac troponin I (cTnI). <abbre...Troponins are muscle proteins that assist muscle contraction regulation. There are two troponins that exist primarily in cardiac muscle: cardiac troponin T (cTnT) and cardiac troponin I (cTnI). <abbrev>CT</abbrev>nI is myocardium specific, whereas cTnT has some small expression in skeletal muscle in addition to cardiac muscle. Because of the high specificity of cTnI and cTnT to cardiac muscle injury, cardiac troponins are used to clinically evaluate for myocardial infarctions in patients with chest pain. However, several other pathologic conditions (cardiac and noncardiac) result in troponin release. Cardiac troponins are detected in serum using monoclonal antibodies or enzyme-linked immunosorbent assays (<abbrev>ELISA</abbrev>s) that are specific for cardiac troponins and do not react with skeletal muscle troponins. Troponin testing options include cTnI, cTnT, and high-sensitivity troponin (hs-Tn). Point-of-care (<abbrev>POC</abbrev>) troponin testing is also available with conflicting reports of quality and usefulness.Read More
Publication Year: 2022
Publication Date: 2022-04-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot