Publication Information

{'id': 'https://openalex.org/W4255345420', 'doi': 'https://doi.org/10.1074/jbc.270.19.11282', 'title': 'Oxidative Decarboxylation of Peptides Catalyzed by Flavoprotein EpiD', 'display_name': 'Oxidative Decarboxylation of Peptides Catalyzed by Flavoprotein EpiD', 'publication_year': 1995, 'publication_date': '1995-05-01', 'ids': {'openalex': 'https://openalex.org/W4255345420', 'doi': 'https://doi.org/10.1074/jbc.270.19.11282', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7744764'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.270.19.11282', 'pdf_url': 'http://www.jbc.org/article/S0021925817501994/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925817501994/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5020865644', 'display_name': 'Thomas Kupke', 'orcid': 'https://orcid.org/0000-0003-2341-1710'}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'Thomas Kupke', 'raw_affiliation_strings': ['Mikrobielle Genetik, Universität Tübingen, Waldhäuserstr. 70/8, 72076 Tübingen, Federal Republic of Germany'], 'affiliations': [{'raw_affiliation_string': 'Mikrobielle Genetik, Universität Tübingen, Waldhäuserstr. 70/8, 72076 Tübingen, Federal Republic of Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027981611', 'display_name': 'Christoph Kempter', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Christoph Kempter', 'raw_affiliation_strings': ['Institut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Federal Republic of Germany'], 'affiliations': [{'raw_affiliation_string': 'Institut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Federal Republic of Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109801971', 'display_name': 'Günther Jung', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Günther Jung', 'raw_affiliation_strings': ['Institut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Federal Republic of Germany'], 'affiliations': [{'raw_affiliation_string': 'Institut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Federal Republic of Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5014079362', 'display_name': 'Friedrich Götz', 'orcid': 'https://orcid.org/0000-0002-4574-0278'}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Friedrich Götz', 'raw_affiliation_strings': ['Mikrobielle Genetik, Universität Tübingen, Waldhäuserstr. 70/8, 72076 Tübingen, Federal Republic of Germany'], 'affiliations': [{'raw_affiliation_string': 'Mikrobielle Genetik, Universität Tübingen, Waldhäuserstr. 70/8, 72076 Tübingen, Federal Republic of Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5020865644'], 'corresponding_institution_ids': ['https://openalex.org/I8087733'], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 3.757, 'has_fulltext': False, 'cited_by_count': 109, 'citation_normalized_percentile': {'value': 0.952102, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '270', 'issue': '19', 'first_page': '11282', 'last_page': '11289'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10911', 'display_name': 'Chemical Synthesis and Analysis', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10911', 'display_name': 'Chemical Synthesis and Analysis', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10404', 'display_name': 'Enzyme Catalysis and Immobilization', 'score': 0.9918, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13127', 'display_name': 'Biotin and Related Studies', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/flavoprotein', 'display_name': 'Flavoprotein', 'score': 0.8241593}, {'id': 'https://openalex.org/keywords/decarboxylation', 'display_name': 'Decarboxylation', 'score': 0.75705653}, {'id': 'https://openalex.org/keywords/oxidative-decarboxylation', 'display_name': 'Oxidative decarboxylation', 'score': 0.7451253}], 'concepts': [{'id': 'https://openalex.org/C71995715', 'wikidata': 'https://www.wikidata.org/wiki/Q78574842', 'display_name': 'Flavoprotein', 'level': 3, 'score': 0.8241593}, {'id': 'https://openalex.org/C2780595602', 'wikidata': 'https://www.wikidata.org/wiki/Q898436', 'display_name': 'Decarboxylation', 'level': 3, 'score': 0.75705653}, {'id': 'https://openalex.org/C2779634684', 'wikidata': 'https://www.wikidata.org/wiki/Q3818578', 'display_name': 'Oxidative decarboxylation', 'level': 3, 'score': 0.7451253}, {'id': 'https://openalex.org/C57600042', 'wikidata': 'https://www.wikidata.org/wiki/Q227564', 'display_name': 'Oxidative phosphorylation', 'level': 2, 'score': 0.70194554}, {'id': 'https://openalex.org/C161790260', 'wikidata': 'https://www.wikidata.org/wiki/Q82264', 'display_name': 'Catalysis', 'level': 2, 'score': 0.60553074}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5959783}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.49191093}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.11843717}], 'mesh': [{'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002262', 'descriptor_name': 'Carboxy-Lyases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005420', 'descriptor_name': 'Flavoproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010088', 'descriptor_name': 'Oxidoreductases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D017354', 'descriptor_name': 'Point Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013212', 'descriptor_name': 'Staphylococcus epidermidis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005420', 'descriptor_name': 'Flavoproteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D005420', 'descriptor_name': 'Flavoproteins', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D005420', 'descriptor_name': 'Flavoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016297', 'descriptor_name': 'Mutagenesis, Site-Directed', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': 'Q000138', 'qualifier_name': 'chemical synthesis', 'is_major_topic': False}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013212', 'descriptor_name': 'Staphylococcus epidermidis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.270.19.11282', 'pdf_url': 'http://www.jbc.org/article/S0021925817501994/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7744764', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.270.19.11282', 'pdf_url': 'http://www.jbc.org/article/S0021925817501994/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.65, 'id': 'https://metadata.un.org/sdg/6', 'display_name': 'Clean water and sanitation'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1024489841', 'https://openalex.org/W1459329288', 'https://openalex.org/W1515765735', 'https://openalex.org/W1603021038', 'https://openalex.org/W1709456377', 'https://openalex.org/W1972439422', 'https://openalex.org/W1973486893', 'https://openalex.org/W1990256494', 'https://openalex.org/W2006310394', 'https://openalex.org/W2006446936', 'https://openalex.org/W2019005479', 'https://openalex.org/W2019744607', 'https://openalex.org/W2033989034', 'https://openalex.org/W2038052339', 'https://openalex.org/W2041719513', 'https://openalex.org/W2054539901', 'https://openalex.org/W2058752732', 'https://openalex.org/W2067424225', 'https://openalex.org/W2072763959', 'https://openalex.org/W2079372854', 'https://openalex.org/W2090161431', 'https://openalex.org/W2092836618', 'https://openalex.org/W2118423669', 'https://openalex.org/W2514574726', 'https://openalex.org/W4229536270', 'https://openalex.org/W4245245408', 'https://openalex.org/W4293247451'], 'related_works': ['https://openalex.org/W808806996', 'https://openalex.org/W2953188457', 'https://openalex.org/W2950812692', 'https://openalex.org/W2949387503', 'https://openalex.org/W2883401967', 'https://openalex.org/W2468788129', 'https://openalex.org/W2059326619', 'https://openalex.org/W2052396922', 'https://openalex.org/W2024057976', 'https://openalex.org/W2021242893'], 'abstract_inverted_index': {'The': [0, 150], 'flavoprotein': [1], 'EpiD': [2, 48, 126, 186], 'catalyzes': [3], 'the': [4, 9, 16, 26, 63, 72, 83, 89, 100, 120, 123, 133, 144, 153, 163, 167, 172], 'COOH-terminal': [5, 17, 155], 'oxidative': [6], 'decarboxylation': [7], 'of': [8, 15, 20, 29, 62, 88, 122, 125, 132, 152, 162, 166], 'lantibiotic': [10], 'precursor': [11], 'peptide': [12, 64, 91], 'EpiA.': [13], 'Variations': [14], 'heptapeptide': [18], 'S1FNSYCC7': [19, 66], 'EpiA': [21, 175, 178], 'were': [22, 67, 75], 'used': [23, 117], 'for': [24], 'determining': [25], 'substrate': [27, 65, 90], 'specificity': [28], 'EpiD.': [30], 'When': [31, 82], 'Cys7': [32], 'was': [33, 49, 92, 116, 136, 148, 158, 179, 187], 'replaced': [34, 93, 107], 'by': [35, 77, 138, 160], 'serine,': [36], 'cysteine-amide,': [37], 'homocysteine,': [38], 'or': [39, 98], 'a': [40], 'thioether': [41], 'amino': [42, 56, 111], 'acid': [43, 57, 112, 154], 'residue,': [44], 'no': [45], 'reaction': [46, 73, 101, 124, 134, 168], 'with': [47, 53, 69, 94, 108, 127], 'observed.': [50], 'Heptapeptide': [51], 'libraries': [52], 'one': [54], 'variable': [55], 'residue': [58, 86, 147], 'at': [59], 'positions': [60], '1-7': [61], 'incubated': [68], 'EpiD,': [70, 177], 'and': [71, 176], 'products': [74, 135], 'identified': [76], 'neutral': [78], 'loss': [79], 'mass': [80, 140], 'spectrometry.': [81], 'penultimate': [84], 'cysteine': [85, 146], 'Cys6': [87], 'Ser,': [95], 'Thr,': [96], 'Ala,': [97], 'Val,': [99], 'still': [102], 'occurred.': [103], 'Tyr5': [104], 'could': [105], 'be': [106], 'other': [109], 'hydrophobic': [110], 'residues.': [113], 'Mass': [114], 'spectrometry': [115], 'to': [118, 181], 'compare': [119], 'kinetics': [121], 'various': [128], 'peptides.': [129], 'Peptide': [130], 'sequencing': [131], 'performed': [137], 'tandem': [139], 'spectrometry,': [141], 'confirming': [142], 'that': [143], 'last': [145], 'modified.': [149], 'removal': [151], 'carboxyl': [156], 'group': [157], 'confirmed': [159], 'determination': [161], 'isoelectric': [164], 'points': [165], 'products.': [169], 'To': [170], 'study': [171], 'interaction': [173], 'between': [174], 'coupled': [180], 'N-hydroxysuccinimide-activated': [182], 'Sepharose': [183], 'HiTrap': [184], 'material;': [185], 'only': [188], 'retarded': [189], 'under': [190], 'reducing': [191], 'conditions.': [192]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4255345420', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-12T19:32:32.229973', 'created_date': '2022-05-12'}