Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4241031629', 'doi': 'https://doi.org/10.1002/(sici)1097-4644(199705)65:2<186::aid-jcb5>3.3.co;2-c', 'title': 'Analysis of epitope structure of PSP94 (prostate secretory protein of 94 amino acids): (II) epitope mapping by monoclonal antibodies', 'display_name': 'Analysis of epitope structure of PSP94 (prostate secretory protein of 94 amino acids): (II) epitope mapping by monoclonal antibodies', 'publication_year': 1997, 'publication_date': '1997-05-01', 'ids': {'openalex': 'https://openalex.org/W4241031629', 'doi': 'https://doi.org/10.1002/(sici)1097-4644(199705)65:2<186::aid-jcb5>3.3.co;2-c'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/(sici)1097-4644(199705)65:2<186::aid-jcb5>3.3.co;2-c', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53807158', 'display_name': 'Journal of Cellular Biochemistry', 'issn_l': '0730-2312', 'issn': ['0730-2312', '1097-4644'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5062501400', 'display_name': 'Jim W. Xuan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I125749732', 'display_name': 'Western University', 'ror': 'https://ror.org/02grkyz14', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I125749732']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Jim W. Xuan', 'raw_affiliation_strings': ['Department of Surgery, University of Western Ontario, London, Ontario'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, University of Western Ontario, London, Ontario', 'institution_ids': ['https://openalex.org/I125749732']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100656520', 'display_name': 'Dongmei Wu', 'orcid': 'https://orcid.org/0000-0003-1398-0434'}, 'institutions': [{'id': 'https://openalex.org/I125749732', 'display_name': 'Western University', 'ror': 'https://ror.org/02grkyz14', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I125749732']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Dongmei Wu', 'raw_affiliation_strings': ['Department of Surgery, University of Western Ontario, London, Ontario'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, University of Western Ontario, London, Ontario', 'institution_ids': ['https://openalex.org/I125749732']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017713972', 'display_name': 'Yuzhen Guo', 'orcid': 'https://orcid.org/0000-0001-5823-7535'}, 'institutions': [{'id': 'https://openalex.org/I125749732', 'display_name': 'Western University', 'ror': 'https://ror.org/02grkyz14', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I125749732']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Yuzhen Guo', 'raw_affiliation_strings': ['Department of Surgery, University of Western Ontario, London, Ontario'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, University of Western Ontario, London, Ontario', 'institution_ids': ['https://openalex.org/I125749732']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049930656', 'display_name': 'Chia L. Huang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I156802259', 'display_name': 'Eastern Virginia Medical School', 'ror': 'https://ror.org/056hr4255', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I156802259']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chia L. Huang', 'raw_affiliation_strings': ['Department of Microbiology and Immunology and the Virginia Prostate Center, Eastern Virginia Medical School and Santara Cancer Institute, Norfolk, Virginia'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology and the Virginia Prostate Center, Eastern Virginia Medical School and Santara Cancer Institute, Norfolk, Virginia', 'institution_ids': ['https://openalex.org/I156802259']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091669057', 'display_name': 'George L. Wright', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I156802259', 'display_name': 'Eastern Virginia Medical School', 'ror': 'https://ror.org/056hr4255', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I156802259']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'George L. Wright', 'raw_affiliation_strings': ['Department of Microbiology and Immunology and the Virginia Prostate Center, Eastern Virginia Medical School and Santara Cancer Institute, Norfolk, Virginia'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology and the Virginia Prostate Center, Eastern Virginia Medical School and Santara Cancer Institute, Norfolk, Virginia', 'institution_ids': ['https://openalex.org/I156802259']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5046888497', 'display_name': 'Joseph L. Chin', 'orcid': 'https://orcid.org/0000-0002-1171-1436'}, 'institutions': [{'id': 'https://openalex.org/I125749732', 'display_name': 'Western University', 'ror': 'https://ror.org/02grkyz14', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I125749732']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Joseph L. Chin', 'raw_affiliation_strings': ['Department of Surgery, University of Western Ontario, London, Ontario'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, University of Western Ontario, London, Ontario', 'institution_ids': ['https://openalex.org/I125749732']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4640, 'currency': 'USD', 'value_usd': 4640, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 55}, 'biblio': {'volume': '65', 'issue': '2', 'first_page': '186', 'last_page': '197'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10725', 'display_name': 'Mechanisms and Applications of RNA Interference', 'score': 0.9918, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11016', 'display_name': 'Therapeutic Antibodies: Development, Engineering, and Applications', 'score': 0.9849, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/polyclonal-antibodies', 'display_name': 'Polyclonal antibodies', 'score': 0.8599131}, {'id': 'https://openalex.org/keywords/linear-epitope', 'display_name': 'Linear epitope', 'score': 0.7836119}, {'id': 'https://openalex.org/keywords/epitope-mapping', 'display_name': 'Epitope mapping', 'score': 0.6766698}, {'id': 'https://openalex.org/keywords/monoclonal-antibodies', 'display_name': 'Monoclonal Antibodies', 'score': 0.469634}], 'concepts': [{'id': 'https://openalex.org/C195616568', 'wikidata': 'https://www.wikidata.org/wiki/Q128711', 'display_name': 'Epitope', 'level': 3, 'score': 0.9731625}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.863112}, {'id': 'https://openalex.org/C956191', 'wikidata': 'https://www.wikidata.org/wiki/Q930144', 'display_name': 'Polyclonal antibodies', 'level': 3, 'score': 0.8599131}, {'id': 'https://openalex.org/C78598654', 'wikidata': 'https://www.wikidata.org/wiki/Q17140316', 'display_name': 'Linear epitope', 'level': 4, 'score': 0.7836119}, {'id': 'https://openalex.org/C2781241564', 'wikidata': 'https://www.wikidata.org/wiki/Q1347450', 'display_name': 'Epitope mapping', 'level': 4, 'score': 0.6766698}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.66014177}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.6278253}, {'id': 'https://openalex.org/C123894998', 'wikidata': 'https://www.wikidata.org/wiki/Q425158', 'display_name': 'Fusion protein', 'level': 4, 'score': 0.576412}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.52883756}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.5019243}, {'id': 'https://openalex.org/C163864487', 'wikidata': 'https://www.wikidata.org/wiki/Q6901461', 'display_name': 'Monoclonal', 'level': 4, 'score': 0.41559565}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.34973007}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.28578582}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.118979394}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.09216681}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/(sici)1097-4644(199705)65:2<186::aid-jcb5>3.3.co;2-c', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53807158', 'display_name': 'Journal of Cellular Biochemistry', 'issn_l': '0730-2312', 'issn': ['0730-2312', '1097-4644'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.48, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3148700447', 'https://openalex.org/W3032815285', 'https://openalex.org/W2976157315', 'https://openalex.org/W2375687856', 'https://openalex.org/W2353483780', 'https://openalex.org/W2353427752', 'https://openalex.org/W2351742909', 'https://openalex.org/W2350907337', 'https://openalex.org/W2348590625', 'https://openalex.org/W2017269580'], 'abstract_inverted_index': {'Journal': [0], 'of': [1, 11, 14, 19, 38, 41, 70, 73, 88, 91, 108, 141, 172, 175, 195, 198, 227, 230, 245, 248, 265, 298, 329, 332, 369, 379, 392, 403, 433, 458, 483, 509, 518, 567, 594, 598, 603, 606, 635, 643, 647, 660, 669, 679], 'Cellular': [2], 'BiochemistryVolume': [3], '65,': [4], 'Issue': [5], '2': [6], 'p.': [7], '186-197': [8, 694], 'Article': [9], 'Analysis': [10], 'epitope': [12, 24, 435, 456, 511, 548, 596, 658], 'structure': [13, 436, 457, 549, 597], 'PSP94': [15, 419, 459, 523, 539, 562, 599, 617, 649], '(prostate': [16], 'secretory': [17], 'protein': [18, 560], '94': [20], 'amino': [21, 573], 'acids):': [22], '(II)': [23], 'mapping': [25], 'by': [26, 63, 81, 99, 130, 163, 183, 220, 238, 256, 287, 320, 340, 488, 527, 553, 584], 'monoclonal': [27, 450, 586, 637, 663], 'antibodies': [28, 451, 587, 638, 664], 'Jim': [29, 34, 186, 191], 'W.': [30, 35, 187, 192], 'Xuan,': [31, 188], 'Corresponding': [32, 189], 'Author': [33, 190], 'Xuan': [36, 193], 'Department': [37, 69, 87, 107, 140, 171, 194, 226, 244, 264, 297, 328], 'Surgery,': [39, 71, 89, 173, 196, 228, 246, 330], 'University': [40, 72, 90, 174, 197, 229, 247, 331], 'Western': [42, 74, 92, 176, 199, 231, 249, 333], 'Ontario,': [43, 56, 75, 93, 177, 200, 213, 232, 250, 334], 'London,': [44, 55, 76, 94, 178, 201, 212, 233, 251, 335], 'OntarioUrology': [45, 202], 'Research': [46, 203], 'Laboratory,': [47, 204], 'London': [48, 205], 'Health': [49, 206], 'Sciences': [50, 207], 'Center,': [51, 116, 149, 208, 273, 306], '375': [52, 209], 'South': [53, 210], 'Street,': [54, 211], 'Canada': [57, 214], 'N6A': [58, 215], '4G5Search': [59, 216], 'for': [60, 78, 96, 127, 160, 180, 217, 235, 253, 284, 317, 337, 428, 439, 506], 'more': [61, 79, 97, 128, 161, 181, 218, 236, 254, 285, 318, 338], 'papers': [62, 80, 98, 129, 162, 182, 219, 237, 255, 286, 319, 339], 'this': [64, 82, 100, 131, 164, 184, 221, 239, 257, 288, 321, 341, 404, 440, 443, 670], 'authorDongmei': [65, 222], 'Wu,': [66, 223], 'Dongmei': [67, 224], 'Wu': [68, 225], 'OntarioSearch': [77, 95, 179, 234, 252, 336], 'authorYuzhen': [83, 240], 'Guo,': [84, 241], 'Yuzhen': [85, 242], 'Guo': [86, 243], 'authorChia': [101, 258], 'L.': [102, 105, 133, 137, 166, 169, 259, 262, 290, 294, 323, 326], 'Huang,': [103, 260], 'Chia': [104, 261], 'Huang': [106, 263], 'Microbiology': [109, 142, 266, 299], 'and': [110, 112, 121, 143, 145, 154, 267, 269, 278, 300, 302, 311, 367, 371, 383, 390, 409, 460, 474, 490, 499, 521, 526, 563, 570, 590, 609, 611, 624, 629], 'Immunology': [111, 144, 268, 301], 'the': [113, 146, 270, 303, 385, 395, 434, 455, 464, 480, 484, 510, 515, 568, 580, 591, 595, 622, 627, 636, 644, 648, 661, 676], 'Virginia': [114, 118, 147, 151, 271, 275, 304, 308], 'Prostate': [115, 148, 272, 305], 'Eastern': [117, 150, 274, 307], 'Medical': [119, 152, 276, 309], 'School': [120, 153, 277, 310], 'Santara': [122, 155, 279, 312], 'Cancer': [123, 156, 280, 313], 'Institute,': [124, 157, 281, 314], 'Norfolk,': [125, 158, 282, 315], 'VirginiaSearch': [126, 159, 283, 316], 'authorGeorge': [132, 289], 'Wright': [134, 138, 291, 295], 'Jr.,': [135, 292], 'George': [136, 293], 'Jr.': [139, 296], 'authorJoseph': [165, 322], 'Chin,': [167, 324], 'Joseph': [168, 325], 'Chin': [170, 327], 'author': [185, 342], 'First': [343], 'published:': [344], '07': [345], 'December': [346], '1998': [347], 'https://doi.org/10.1002/(SICI)1097-4644(199705)65:2<186::AID-JCB5>3.0.CO;2-QCitations:': [348], '8AboutPDF': [349], 'ToolsRequest': [350], 'permissionExport': [351], 'citationAdd': [352], 'to': [353, 375, 398, 423, 453, 461, 542, 674], 'favoritesTrack': [354], 'citation': [355], 'ShareShare': [356], 'Give': [357], 'accessShare': [358, 361], 'full': [359], 'text': [360], 'full-text': [362, 377, 401], 'accessPlease': [363], 'review': [364], 'our': [365, 468], 'Terms': [366, 389], 'Conditions': [368, 391], 'Use': [370], 'check': [372], 'box': [373], 'below': [374, 397], 'share': [376, 399], 'version': [378, 402], 'article.I': [380], 'have': [381, 446, 543], 'read': [382], 'accept': [384], 'Wiley': [386], 'Online': [387], 'Library': [388], 'UseShareable': [393], 'LinkUse': [394], 'link': [396], 'a': [400, 415, 425, 544, 654], 'article': [405], 'with': [406, 463, 524, 531, 561, 564], 'your': [407], 'friends': [408], 'colleagues.': [410], 'Learn': [411], 'more.Copy': [412], 'URL': [413], 'Share': [414], 'linkShare': [416], 'onFacebookTwitterLinkedInRedditWechat': [417], 'Abstract': [418], 'has': [420], 'shown': [421, 541], 'potential': [422], 'be': [424], 'serum': [426], 'biomarker': [427], 'evaluating': [429], 'prostate': [430], 'cancer.': [431], 'Studies': [432], 'is': [437], 'crucial': [438], 'endeavour.': [441], 'In': [442], 'article,': [444], 'we': [445, 478, 551], 'used': [447], '15': [448, 485, 502, 585, 662], 'different': [449, 581], '(MAb)': [452], 'analyse': [454], 'compare': [462], 'results': [465, 668], 'obtained': [466], 'from': [467], 'previous': [469], 'work': [470], 'using': [471], 'polyclonal': [472, 554], 'antibody': [473], 'recombinant': [475, 519, 557, 607], 'PSP94.': [476, 680], 'Firstly,': [477], 'determined': [479], 'relative': [481], 'activities': [482, 517], 'MAb': [486], 'population': [487], 'direct': [489, 604], 'competitive': [491, 613], 'ELISA.': [492], 'The': [493, 667], 'two': [494], 'predominant': [495], 'MAbs': [496, 503, 532], '(MAb': [497], 'PSP-6': [498], '-19)': [500], 'in': [501, 533, 535, 576], 'were': [504, 588], 'selected': [505], 'further': [507], 'studies': [508], 'structure.': [512], 'By': [513], 'comparing': [514, 528], 'binding': [516, 614, 642], 'GST-PSP94': [520], 'natural': [522, 616], 'MAbs,': [525], 'their': [529, 612], 'affinity': [530], 'an': [534, 657], 'vitro': [536], 'denaturing': [537], 'experiment,': [538], 'was': [540, 600, 665], 'similar,': [545], 'prevalently': [546], 'linear': [547], 'as': [550, 653], 'demonstrated': [552], 'antibody.': [555], 'Using': [556, 651], 'GST': [558], 'fusion': [559], 'each': [565], 'half': [566], 'N-': [569, 623], 'C-terminal': [571], '47': [572], 'acids': [574], '(GST-PSP-N47/C47)': [575], 'E.': [577], 'coli': [578], 'cells,': [579], 'epitopes': [582], 'recognized': [583], 'delineated': [589], 'polar': [592], 'distribution': [593], 'characterized.': [601], 'Results': [602], 'ELISA': [605], 'N47': [608], 'C47': [610], 'against': [615], '(competitive': [618], 'ELISA)': [619], 'showed': [620, 640], 'that': [621], 'C-termini': [625], 'represent': [626], 'immuno-dominant': [628], 'immuno-recessive': [630], 'area': [631], 'separately.': [632], 'A': [633], 'majority': [634], '(12/15)': [639], 'preferential': [641], 'N-terminal': [645], 'sequence': [646], 'protein.': [650], 'GST-PSP-N47': [652], 'standard': [655], 'protein,': [656], 'map': [659], 'obtained.': [666], 'study': [671], 'will': [672], 'help': [673], 'define': [675], 'clinical': [677], 'utility': [678], 'J.': [681], 'Cell.': [682], 'Biochem.': [683], '65:186–197.': [684], '©': [685], '1997': [686], 'Wiley-Liss,': [687], 'Inc.': [688], 'Citing': [689], 'Literature': [690], 'Volume65,': [691], 'Issue2May': [692], '1997Pages': [693], 'RelatedInformation': [695]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4241031629', 'counts_by_year': [], 'updated_date': '2024-09-18T05:43:45.936626', 'created_date': '2022-05-12'}