Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4212773757', 'doi': 'https://doi.org/10.1016/j.eururo.2022.01.043', 'title': 'Phase II Study of Neoadjuvant Nivolumab in Patients with Locally Advanced Clear Cell Renal Cell Carcinoma Undergoing Nephrectomy', 'display_name': 'Phase II Study of Neoadjuvant Nivolumab in Patients with Locally Advanced Clear Cell Renal Cell Carcinoma Undergoing Nephrectomy', 'publication_year': 2022, 'publication_date': '2022-06-01', 'ids': {'openalex': 'https://openalex.org/W4212773757', 'doi': 'https://doi.org/10.1016/j.eururo.2022.01.043', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/35183395'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.eururo.2022.01.043', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96871409', 'display_name': 'European Urology', 'issn_l': '0302-2838', 'issn': ['0302-2838', '1421-993X', '1873-7560'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156541', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5073268337', 'display_name': 'Maria I. Carlo', 'orcid': 'https://orcid.org/0000-0002-4786-7408'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Maria I. Carlo', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008544568', 'display_name': 'Kyrollis Attalla', 'orcid': 'https://orcid.org/0000-0002-4707-9663'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kyrollis Attalla', 'raw_affiliation_strings': ['Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032462026', 'display_name': 'Yousef Mazaheri', 'orcid': 'https://orcid.org/0000-0002-8493-1608'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yousef Mazaheri', 'raw_affiliation_strings': ['Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047795118', 'display_name': 'Sounak Gupta', 'orcid': 'https://orcid.org/0000-0001-5163-6955'}, 'institutions': [{'id': 'https://openalex.org/I4210125099', 'display_name': 'Mayo Clinic in Arizona', 'ror': 'https://ror.org/03jp40720', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1330342723', 'https://openalex.org/I4210125099']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sounak Gupta', 'raw_affiliation_strings': ['Department of Pathology, Mayo Clinic, Rochester, MN, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Mayo Clinic, Rochester, MN, USA', 'institution_ids': ['https://openalex.org/I4210125099']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081003182', 'display_name': 'Onur Yıldırım', 'orcid': 'https://orcid.org/0000-0002-1586-1933'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Onur Yildirim', 'raw_affiliation_strings': ['Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030257639', 'display_name': 'Samuel Murray', 'orcid': 'https://orcid.org/0000-0003-0074-6462'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Samuel J. Murray', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005184646', 'display_name': 'Devyn Taylor Coskey', 'orcid': 'https://orcid.org/0000-0003-1663-2398'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Devyn T. Coskey', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019538697', 'display_name': 'Ritesh R. Kotecha', 'orcid': 'https://orcid.org/0000-0002-0223-3479'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ritesh Kotecha', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018855400', 'display_name': 'Chung‐Han Lee', 'orcid': 'https://orcid.org/0000-0001-5511-0635'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chung-Han Lee', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018531384', 'display_name': 'Darren R. Feldman', 'orcid': 'https://orcid.org/0000-0003-2424-4635'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Darren R. Feldman', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030709443', 'display_name': 'Paul Russo', 'orcid': 'https://orcid.org/0000-0001-7487-6783'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Paul Russo', 'raw_affiliation_strings': ['Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069656105', 'display_name': 'Sujata Patil', 'orcid': 'https://orcid.org/0000-0003-1706-5321'}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sujata Patil', 'raw_affiliation_strings': ['Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA', 'institution_ids': ['https://openalex.org/I1316902750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059063118', 'display_name': 'Robert J. Motzer', 'orcid': 'https://orcid.org/0000-0001-6925-2327'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert J. Motzer', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081581200', 'display_name': 'Jonathan Coleman', 'orcid': 'https://orcid.org/0000-0002-6428-7835'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jonathan A. Coleman', 'raw_affiliation_strings': ['Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034663203', 'display_name': 'Jeremy C. Durack', 'orcid': 'https://orcid.org/0000-0002-0672-9586'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jeremy C. Durack', 'raw_affiliation_strings': ['Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003119579', 'display_name': 'Ying‐Bei Chen', 'orcid': 'https://orcid.org/0000-0001-5207-3648'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ying-Bei Chen', 'raw_affiliation_strings': ['Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082504366', 'display_name': 'Oğuz Akın', 'orcid': 'https://orcid.org/0000-0002-2041-6199'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Oguz Akin', 'raw_affiliation_strings': ['Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089094298', 'display_name': 'A. Ari Hakimi', 'orcid': 'https://orcid.org/0000-0002-0930-8824'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'A. Ari Hakimi', 'raw_affiliation_strings': ['Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5091859782', 'display_name': 'Martin H. Voss', 'orcid': 'https://orcid.org/0000-0003-0551-5807'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Martin H. Voss', 'raw_affiliation_strings': ['Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5089094298', 'https://openalex.org/A5091859782'], 'corresponding_institution_ids': ['https://openalex.org/I1334819555', 'https://openalex.org/I1334819555'], 'apc_list': {'value': 5250, 'currency': 'USD', 'value_usd': 5250, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 8.088, 'has_fulltext': False, 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.999972, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '81', 'issue': '6', 'first_page': '570', 'last_page': '573'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10449', 'display_name': 'Renal Cell Carcinoma', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10449', 'display_name': 'Renal Cell Carcinoma', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10458', 'display_name': 'Diagnosis and Treatment of Bladder Cancer', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/kidney-cancer', 'display_name': 'Kidney cancer', 'score': 0.718328}, {'id': 'https://openalex.org/keywords/neoadjuvant-therapy', 'display_name': 'Neoadjuvant Therapy', 'score': 0.540862}, {'id': 'https://openalex.org/keywords/immune-checkpoint-blockade', 'display_name': 'Immune Checkpoint Blockade', 'score': 0.514826}, {'id': 'https://openalex.org/keywords/treatment', 'display_name': 'Treatment', 'score': 0.509286}, {'id': 'https://openalex.org/keywords/nephrology', 'display_name': 'Nephrology', 'score': 0.5066629}, {'id': 'https://openalex.org/keywords/renal-cell-carcinoma', 'display_name': 'Renal Cell Carcinoma', 'score': 0.502751}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.97029626}, {'id': 'https://openalex.org/C2777472916', 'wikidata': 'https://www.wikidata.org/wiki/Q1164529', 'display_name': 'Renal cell carcinoma', 'level': 2, 'score': 0.8888604}, {'id': 'https://openalex.org/C2780030458', 'wikidata': 'https://www.wikidata.org/wiki/Q7041828', 'display_name': 'Nivolumab', 'level': 4, 'score': 0.87558997}, {'id': 'https://openalex.org/C2780227381', 'wikidata': 'https://www.wikidata.org/wiki/Q1357376', 'display_name': 'Nephrectomy', 'level': 3, 'score': 0.86498314}, {'id': 'https://openalex.org/C2781068499', 'wikidata': 'https://www.wikidata.org/wiki/Q3242950', 'display_name': 'Kidney cancer', 'level': 3, 'score': 0.718328}, {'id': 'https://openalex.org/C54847362', 'wikidata': 'https://www.wikidata.org/wiki/Q177635', 'display_name': 'Nephrology', 'level': 2, 'score': 0.5066629}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.49691275}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.42952824}, {'id': 'https://openalex.org/C126894567', 'wikidata': 'https://www.wikidata.org/wiki/Q105650', 'display_name': 'Urology', 'level': 1, 'score': 0.42198604}, {'id': 'https://openalex.org/C2778653478', 'wikidata': 'https://www.wikidata.org/wiki/Q1054718', 'display_name': 'Kidney disease', 'level': 2, 'score': 0.41627702}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.39455676}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.36661124}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.35247493}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.32364392}, {'id': 'https://openalex.org/C2777701055', 'wikidata': 'https://www.wikidata.org/wiki/Q1427096', 'display_name': 'Immunotherapy', 'level': 3, 'score': 0.31719863}], 'mesh': [{'descriptor_ui': 'D002292', 'descriptor_name': 'Carcinoma, Renal Cell', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007680', 'descriptor_name': 'Kidney Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020360', 'descriptor_name': 'Neoadjuvant Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009392', 'descriptor_name': 'Nephrectomy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077594', 'descriptor_name': 'Nivolumab', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.eururo.2022.01.043', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96871409', 'display_name': 'European Urology', 'issn_l': '0302-2838', 'issn': ['0302-2838', '1421-993X', '1873-7560'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156541', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/35183395', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156541', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'score': 0.84, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W2017206151', 'https://openalex.org/W2044465660', 'https://openalex.org/W2791483720', 'https://openalex.org/W2972960135', 'https://openalex.org/W2997030355', 'https://openalex.org/W3083223141', 'https://openalex.org/W3094602543', 'https://openalex.org/W3164493404', 'https://openalex.org/W3168189500', 'https://openalex.org/W3196207248', 'https://openalex.org/W4229029457'], 'related_works': ['https://openalex.org/W4310753920', 'https://openalex.org/W4283731517', 'https://openalex.org/W4212804027', 'https://openalex.org/W3135487424', 'https://openalex.org/W3132893788', 'https://openalex.org/W2981065291', 'https://openalex.org/W2977436503', 'https://openalex.org/W2966932534', 'https://openalex.org/W2955056171', 'https://openalex.org/W2792937256'], 'abstract_inverted_index': {'Immune': [0], 'checkpoint': [1], 'inhibitor': [2], 'therapy': [3], 'improves': [4], 'survival': [5], 'in': [6, 21, 42], 'patients': [7, 22, 43, 50, 112, 140, 146, 211, 232], 'with': [8, 23, 119, 198, 212], 'metastatic': [9], 'renal': [10], 'cell': [11, 121], 'carcinoma': [12], '(RCC)': [13], 'but': [14], 'has': [15], 'not': [16], 'been': [17], 'studied': [18], 'well': [19], 'preoperatively': [20], 'localized': [24, 47, 213], 'disease': [25], 'undergoing': [26, 44], 'nephrectomy.': [27], 'We': [28, 206], 'conducted': [29], 'a': [30, 52, 60, 228], 'single-center': [31], 'study': [32], 'to': [33, 73, 135, 187, 220, 222, 237], 'evaluate': [34], 'the': [35, 95, 160, 208, 238], 'safety': [36], 'and': [37, 91, 106, 133, 153, 175, 191, 197, 244], 'feasibility': [38], 'of': [39, 55, 97, 110, 131, 202, 231], 'neoadjuvant': [40], 'nivolumab': [41, 65, 132, 148], 'nephrectomy': [45, 136, 188], 'for': [46, 69, 149, 210], 'RCC.': [48], 'Eligible': [49], 'had': [51, 155, 234], '>20%': [53], 'risk': [54], 'recurrence,': [56], 'as': [57, 81, 94, 158], 'estimated': [58], 'by': [59, 104], 'preoperative': [61], 'nomogram.': [62], 'Patients': [63], 'received': [64, 126, 217], 'every': [66], '2': [67], 'wk': [68], 'four': [70, 143, 154], 'treatments': [71, 86], 'prior': [72, 186, 219], 'surgery.': [74], 'The': [75], 'primary': [76], 'endpoints': [77], 'were': [78, 102, 123], 'feasibility,': [79], 'defined': [80, 93], 'completing': [82], 'at': [83, 127], 'least': [84, 128], 'three': [85], 'without': [87, 137, 193], 'significant': [88, 194], 'surgical': [89, 98, 156, 195], 'delay,': [90], 'safety,': [92], 'rate': [96, 201], 'complications.': [99], 'Treatment': [100], 'effects': [101], 'assessed': [103], 'radiomics': [105], 'immunohistochemistry.': [107], 'A': [108], 'total': [109], '18': [111], '(11': [113], 'men;': [114], 'median': [115], 'age': [116], '60': [117], 'yr)': [118], 'clear': [120], 'RCC': [122], 'enrolled.': [124], 'All': [125], 'one': [129], 'dose': [130], 'proceeded': [134], 'delay;': [138], '16/18': [139], 'completed': [141], 'all': [142], 'doses.': [144], 'Two': [145], 'discontinued': [147], 'immune-related': [150, 203], 'adverse': [151, 204], 'events,': [152], 'complications': [157], 'per': [159], 'Clavien-Dindo': [161], 'classification.': [162], 'Integrated': [163], 'pathology': [164], 'plus': [165], 'radiomic': [166], 'analysis': [167], 'demonstrated': [168], 'an': [169, 199], 'association': [170], 'between': [171], 'post-treatment': [172], 'immune': [173], 'infiltration': [174], 'low': [176], 'entropy': [177], 'apparent': [178], 'diffusion': [179], 'coefficient': [180], 'on': [181], 'magnetic': [182], 'resonance': [183], 'imaging.': [184], 'Nivolumab': [185], 'was': [189], 'safe': [190, 243], 'feasible,': [192], 'delays': [196], 'expected': [200], 'events.': [205], 'evaluated': [207], 'outcomes': [209], 'kidney': [214, 225], 'cancer': [215, 235], 'who': [216, 233], 'immunotherapy': [218], 'surgery': [221], 'remove': [223], 'their': [224], 'tumor.': [226], 'In': [227], 'small': [229], 'group': [230], 'confined': [236], 'kidney,': [239], 'this': [240], 'approach': [241], 'appeared': [242], 'feasible.': [245]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4212773757', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 5}], 'updated_date': '2024-09-01T09:39:09.992213', 'created_date': '2022-02-24'}