Publication Information

{'id': 'https://openalex.org/W4205330301', 'doi': 'https://doi.org/10.1126/stke.2000.23.tw1', 'title': 'Endocytosis, Cleavage, and Signaling by Notch', 'display_name': 'Endocytosis, Cleavage, and Signaling by Notch', 'publication_year': 2000, 'publication_date': '2000-03-14', 'ids': {'openalex': 'https://openalex.org/W4205330301', 'doi': 'https://doi.org/10.1126/stke.2000.23.tw1'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/stke.2000.23.tw1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210180107', 'display_name': 'Science s STKE', 'issn_l': '1525-8882', 'issn': ['1525-8882'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 58}, 'biblio': {'volume': '2000', 'issue': '23', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9541, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9541, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10423', 'display_name': 'Neurobiology and Insect Physiology Research', 'score': 0.9069, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/notch-proteins', 'display_name': 'Notch proteins', 'score': 0.7785538}, {'id': 'https://openalex.org/keywords/hes3-signaling-axis', 'display_name': 'Hes3 signaling axis', 'score': 0.6811421}, {'id': 'https://openalex.org/keywords/cyclin-dependent-kinase-8', 'display_name': 'Cyclin-dependent kinase 8', 'score': 0.57709485}, {'id': 'https://openalex.org/keywords/hairless', 'display_name': 'Hairless', 'score': 0.41078907}], 'concepts': [{'id': 'https://openalex.org/C161879069', 'wikidata': 'https://www.wikidata.org/wiki/Q904082', 'display_name': 'Notch signaling pathway', 'level': 3, 'score': 0.89609617}, {'id': 'https://openalex.org/C28005876', 'wikidata': 'https://www.wikidata.org/wiki/Q189814', 'display_name': 'Endocytosis', 'level': 3, 'score': 0.8930377}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.7804328}, {'id': 'https://openalex.org/C202769670', 'wikidata': 'https://www.wikidata.org/wiki/Q4045508', 'display_name': 'Notch proteins', 'level': 4, 'score': 0.7785538}, {'id': 'https://openalex.org/C65114990', 'wikidata': 'https://www.wikidata.org/wiki/Q5745269', 'display_name': 'Hes3 signaling axis', 'level': 4, 'score': 0.6811421}, {'id': 'https://openalex.org/C116227048', 'wikidata': 'https://www.wikidata.org/wiki/Q18021243', 'display_name': 'Cyclin-dependent kinase 8', 'level': 4, 'score': 0.57709485}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5153022}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.49865127}, {'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.46706945}, {'id': 'https://openalex.org/C24530287', 'wikidata': 'https://www.wikidata.org/wiki/Q424204', 'display_name': 'Transmembrane protein', 'level': 3, 'score': 0.42760563}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.41230392}, {'id': 'https://openalex.org/C2779156968', 'wikidata': 'https://www.wikidata.org/wiki/Q17141495', 'display_name': 'Hairless', 'level': 2, 'score': 0.41078907}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.30646503}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.12830657}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/stke.2000.23.tw1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210180107', 'display_name': 'Science s STKE', 'issn_l': '1525-8882', 'issn': ['1525-8882'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3211904497', 'https://openalex.org/W2886988419', 'https://openalex.org/W2755269699', 'https://openalex.org/W2020753350', 'https://openalex.org/W2018868898', 'https://openalex.org/W2007921174', 'https://openalex.org/W1999615839', 'https://openalex.org/W1989474037', 'https://openalex.org/W1965060648', 'https://openalex.org/W1543633454'], 'abstract_inverted_index': {'Notch': [0, 14, 27, 46, 56, 73, 97, 110, 128, 158], 'and': [1, 10, 67, 72, 75, 99, 121, 135, 145, 154], 'Delta': [2, 52, 71, 89, 104], 'are': [3], 'transmembrane': [4], 'proteins': [5], 'that': [6, 43, 105], 'interact': [7], 'as': [8], 'receptor': [9, 152], 'ligand.': [11], 'Signaling': [12], 'by': [13], 'involves': [15], 'the': [16, 19, 25, 55, 60, 65, 118, 133, 157], 'cleavage': [17, 98], 'of': [18, 31, 51, 70, 127, 137], 'intracellular': [20, 74], 'domain,': [21], 'which': [22], 'acts': [23], 'with': [24, 54, 80], 'primary': [26], 'signal': [28], 'transducer': [29], 'Suppressor': [30], 'Hairless': [32], 'to': [33, 88, 92, 95], 'regulate': [34], 'transcription': [35], 'in': [36, 78, 82, 85, 103, 114, 117, 156], 'Drosophila': [37], '.': [38], 'Parks': [39], 'et': [40], 'al.': [41], 'found': [42], 'signaling': [44, 116], 'through': [45], 'was': [47], 'dependent': [48, 130], 'on': [49, 131], 'endocytosis': [50, 107, 136, 150], 'complexed': [53], 'extracellular': [57, 76], 'domain': [58], 'into': [59], 'Delta-expressing': [61], 'cell.': [62], 'They': [63], 'analyzed': [64], 'function': [66], 'subcellular': [68], 'distribution': [69], 'domains': [77], 'flies': [79], 'mutations': [81, 102], 'genes': [83], 'involved': [84], 'endocytosis.': [86], 'Binding': [87], 'appeared': [90], 'not': [91], 'be': [93], 'sufficient': [94], 'initiate': [96], 'signaling,': [100], 'because': [101], 'disrupted': [106], 'without': [108], 'affecting': [109], 'binding': [111, 134], 'were': [112], 'blocked': [113], 'Delta-Notch': [115], 'developing': [119], 'eye': [120], 'wing': [122], 'vein.': [123], 'Thus,': [124], 'proper': [125], 'processing': [126], 'is': [129], 'both': [132], 'Delta.': [138], 'Parks,': [139], 'A.L.,': [140], 'Klueg,': [141], 'K.M.,': [142], 'Stout,': [143], 'J.R,': [144], 'Muskavitch,': [146], 'M.A.T.': [147], '(2000)': [148], 'Ligand': [149], 'drives': [151], 'dissociation': [153], 'activation': [155], 'pathway.': [159], 'Development': [160], '127': [161], ':': [162], '1373-1385.': [163], '[Online': [164], 'Journal]': [165]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4205330301', 'counts_by_year': [], 'updated_date': '2024-12-15T07:06:15.946533', 'created_date': '2022-01-26'}